Myeloid Endoplasmic Reticulum Resident Chaperone GP96 Facilitates Inflammation and Steatosis in Alcohol‐Associated Liver Disease

Anuradha Ratna, Arlene Lim, Zihai Li, Josepmaria Argemi, Ramon Bataller, Gabriela Chiosis, Pranoti Mandrekar – 21 May 2021 – Cellular stress–mediated chaperones are linked to liver macrophage activation and inflammation in alcohol‐associated liver disease (ALD). In this study, we investigate the role of endoplasmic reticulum (ER) resident stress chaperone GP96/HSP90B1/GRP94, paralog of the HSP90 family, in ALD pathogenesis. We hypothesize that ER resident chaperone, heat shock protein GP96, plays a crucial role in alcohol‐associated liver inflammation and contributes to liver injury.

Combination of Model for End‐Stage Liver Disease and Lactate Predicts Death in Patients Treated With Salvage Transjugular Intrahepatic Portosystemic Shunt for Refractory Variceal Bleeding

Aurélie Walter, Marika Rudler, Pol Olivas, Lucile Moga, Eric Trépo, Marie Angèle Robic, Isabelle Ollivier‐Hourmand, Anna Baiges, Olivier Sutter, Charlotte Bouzbib, Jean Marie Peron, Vincent Le Pennec, Nathalie Ganne‐Carrié, Juan Carlos Garcia‐Pagán, Maxime Mallet, Hélène Larrue, Thong Dao, Dominique Thabut, Virginia Hernández‐Gea, Jean‐Charles Nault, Christophe Bureau, Manon Allaire, the Salvage TIPS Group – 20 May 2021

Standardized Feeding Protocol Improves Delivery and Acceptance of Enteral Nutrition in Children Immediately After Liver Transplantation

Mar Miserachs, Penni Kean, Lori Tuira, Yasser Al Nasser, Maria De Angelis, Krista Van Roestel, Anand Ghanekar, Mark Cattral, Marialena Mouzaki, Vicky Lee Ng, Haifa Mtaweh, Yaron Avitzur – 20 May 2021 – Delivery of adequate nutrition after liver transplantation (LT) surgery is an important goal of postoperative care. Existing guidelines recommend early enteral nutrition after abdominal surgery and in the child who is critically ill but data on nutritional interventions after LT in children are sparse.

Type 2 Autoimmune Hepatitis and Nonadherence to Medication Correlate With Premature Birth and Risk of Postpartum Flare

Kathryn Olsen, James Hodson, Vincenzo Ronca, Amber G. Bozward, Jennifer Hayden, Grace Wootton, Matthew Armstrong, David H. Adams, Omar El‐Sherif, James Ferguson, Ellen Knox, Tracey Johnston, Fiona Thompson, Ye Htun Oo – 20 May 2021 – Autoimmune hepatitis (AIH) is an immune‐mediated chronic liver disease that affects all ages, including women of childbearing age. Optimal management during pregnancy is poorly defined.

Type 2 Autoimmune Hepatitis and Nonadherence to Medication Correlate With Premature Birth and Risk of Postpartum Flare

Kathryn Olsen, James Hodson, Vincenzo Ronca, Amber G. Bozward, Jennifer Hayden, Grace Wootton, Matthew Armstrong, David H. Adams, Omar El‐Sherif, James Ferguson, Ellen Knox, Tracey Johnston, Fiona Thompson, Ye Htun Oo – 20 May 2021 – Autoimmune hepatitis (AIH) is an immune‐mediated chronic liver disease that affects all ages, including women of childbearing age. Optimal management during pregnancy is poorly defined.

Subscribe to