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Shalimar, Mohammed Faisal Sheikh, Rajeshwar P. Mookerjee, Banwari Agarwal, Subrat Kumar Acharya, Rajiv Jalan – 11 May 2019
Rehabilitation of Discarded Steatotic Livers Using Ex Situ Normothermic Machine Perfusion: A Future Source of Livers for Transplantation
Siavash Raigani, James F. Markmann, Heidi Yeh – 11 May 2019
Fibrosing Cholestatic Hepatitis–Like Syndrome in an Immunocompetent Patient With an Acute Flare of Chronic Hepatitis B
Nigel Sutherland, Christopher Foong Dhin Li Wai Suen, Christopher Mills, Julie Lokan, Marie Sinclair – 11 May 2019
Fibrosing Cholestatic Hepatitis–Like Syndrome in an Immunocompetent Patient With an Acute Flare of Chronic Hepatitis B
Nigel Sutherland, Christopher Foong Dhin Li Wai Suen, Christopher Mills, Julie Lokan, Marie Sinclair – 11 May 2019
Integrated Omics Reveals Tollip as an Regulator and Therapeutic Target for Hepatic Ischemia‐Reperfusion Injury in Mice
Zhen‐Zhen Yan, Yong‐Ping Huang, Xin Wang, Hai‐Ping Wang, Fei Ren, Rui‐Feng Tian, Xu Cheng, Jie Cai, Yan Zhang, Xue‐Yong Zhu, Zhi‐Gang She, Xiao‐Jing Zhang, Zan Huang, Hongliang Li – 11 May 2019 – Hepatic ischemia‐reperfusion (IR) injury is the leading cause of liver dysfunction and failure after liver resection or transplantation and lacks effective therapeutic strategies. Here, we applied a systematic proteomic analysis to identify the prominent contributors to IR‐induced liver damage and promising therapeutic targets for this condition.
Letter to Editor: Prognostic Role of Ammonia in Patients With Cirrhosis
Narendra S. Choudhary, Sanjiv Saigal, Neeraj Saraf, Arvinder S. Soin – 11 May 2019
Deficient IL‐6/Stat3 Signaling, High TLR7, and Type I Interferons in Early Human Alcoholic Liver Disease: A Triad for Liver Damage and Fibrosis
Peter Stärkel, Bernd Schnabl, Sophie Leclercq, Mina Komuta, Ramon Bataller, Josepmaria Argemi, Elena Palma, Shilpa Chokshi, Claus Hellerbrand, Luca Maccioni, Nicolas Lanthier, Isabelle Leclercq – 10 May 2019 – Mechanisms underlying alcohol‐induced liver injury and its progression still remain incompletely understood. Animal models can only address some aspects of the pathophysiology that requires studies directly in humans, which are scarce.
Deficient IL‐6/Stat3 Signaling, High TLR7, and Type I Interferons in Early Human Alcoholic Liver Disease: A Triad for Liver Damage and Fibrosis
Peter Stärkel, Bernd Schnabl, Sophie Leclercq, Mina Komuta, Ramon Bataller, Josepmaria Argemi, Elena Palma, Shilpa Chokshi, Claus Hellerbrand, Luca Maccioni, Nicolas Lanthier, Isabelle Leclercq – 10 May 2019 – Mechanisms underlying alcohol‐induced liver injury and its progression still remain incompletely understood. Animal models can only address some aspects of the pathophysiology that requires studies directly in humans, which are scarce.
LiverLearning®: 2019 Webinar: Management of NAFLD: Integrating Strategies from Obesity Medicine into Clinical Practice
NAFLD is an increasing public health crisis. Although there are no FDA approved medications for the treatment of NAFLD, it is well established that weight loss can improve the metabolic and histologic parameters associated with NAFLD. This webinar will identify key lifestyle changes, pharmacotherapy, and the role of bariatric surgery in obesity management in patients with NAFLD.
Focal Adhesion Kinase and β‐Catenin Cooperate to Induce Hepatocellular Carcinoma
Na Shang, Hao Wang, Thomas Bank, Aldeb Perera, Cara Joyce, Gina Kuffel, Michael J. Zilliox, Scott J. Cotler, Xianzhong Ding, Asha Dhanarajan, Peter Breslin, Wei Qiu – 9 May 2019 – There is an urgent need to understand the molecular signaling pathways that drive or mediate the development of hepatocellular carcinoma (HCC). The focal adhesion kinase (FAK) gene protein tyrosine kinase 2 is amplified in 16.4% of The Cancer Genome Atlas HCC specimens, and its amplification leads to increased FAK mRNA expression.