Direct‐acting antivirals during or after immunochemotherapy in hepatitis C virus–positive diffuse large B‐cell lymphomas
Michele Merli, Marco Frigeni, Manuel Gotti, Paolo Grossi, Raffaele Bruno, Francesco Passamonti, Luca Arcaini – 5 April 2017
How to identify patients with advanced liver disease in the community?
Terry Cheuk‐Fung Yip, Vincent Wai‐Sun Wong – 5 April 2017
FABP1 as a novel potential biomarker for predicting mortality in acetaminophen‐induced acute liver failure
Heng Fan, Jian‐hua Zhu – 2 April 2017
Overt acute hepatitis B is more severe in female patients
Ming‐Ling Chang, Yun‐Fan Liaw – 2 April 2017
Hepatitis C viral load, genotype, and increased risk of developing end‐stage renal disease: REVEAL‐HCV study
Tai‐Shuan Lai, Mei‐Hsuan Lee, Hwai‐I Yang, San‐Lin You, Sheng‐Nan Lu, Li‐Yu Wang, Yong Yuan, Gilbert L'Italien, Kuo‐Liong Chien, Chien‐Jen Chen, for the REVEAL‐HCV Study Group – 2 April 2017 – The association between hepatitis C virus (HCV) infection and end‐stage renal disease (ESRD) remains controversial without considering the role of HCV viral load and genotype. This study aimed to determine whether HCV RNA level and genotype affect the risk of developing ESRD.
REPLY:
Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Christopher F. Rose, For the US Acute Liver Failure Study Group – 2 April 2017
Overt acute hepatitis B is more severe in female patients
Ming‐Ling Chang, Yun‐Fan Liaw – 2 April 2017
Allogeneic bone marrow–derived mesenchymal stromal cells for hepatitis B virus–related acute‐on‐chronic liver failure: A randomized controlled trial
Bing‐liang Lin, Jun‐feng Chen, Wei‐hong Qiu, Ke‐wei Wang, Dong‐ying Xie, Xiao‐yong Chen, Qiu‐li Liu, Liang Peng, Jian‐guo Li, Yong‐yu Mei, Wei‐zhen Weng, Yan‐wen Peng, Hui‐juan Cao, Jun‐qiang Xie, Shi‐bin Xie, Andy Peng Xiang, Zhi‐liang Gao – 1 April 2017 – Mortality from hepatitis B virus (HBV)–related acute‐on‐chronic liver failure (ACLF) is high due to limited treatment options. Preclinical and clinical investigations have proved that treatment with mesenchymal stromal cells (MSCs) is beneficial for recovery from liver injury.
Crosstalk of LKB1‐regulated and PTEN‐regulated signals in liver morphogenesis and tumor development in mice
Chengyou Jia, Vivian Medina, Chenchang Liu, Lina He, Daohai Qian, Taojian Tu, Curtis T. Okamoto, Bangyan L. Stiles – 1 April 2017 – Liver kinase B 1 (LKB1 or STK11) and phosphatase and tensin homologue deleted on chromosome 10 (PTEN) are two tumor suppressors that regulate the mammalian target of rapamycin signaling pathway. Deletion studies show that loss of either Lkb1 (Lkb+/–) or Pten (PtenloxP/loxP; Alb‐Cre+) leads to liver injury and development of hepatocarcinoma. In this study, we investigated the crosstalk of LKB1 and PTEN loss during tumorigenesis and liver development.
Clinical criteria are critical to diagnosing alcoholic hepatitis
Ewan Forrest – 1 April 2017