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Po‐Da Chen, Yao‐Ming Wu – 13 April 2017
A novel role for CRTC2 in hepatic cholesterol synthesis through SREBP‐2
Yujie Li, Yongfeng Song, Meng Zhao, Yanjing Guo, Chunxiao Yu, Wenbin Chen, Shanshan Shao, Chao Xu, Xinli Zhou, Lifang Zhao, Zhenhai Zhang, Tao Bo, Yu Xia, Christopher G. Proud, Xuemin Wang, Li Wang, Jiajun Zhao, Ling Gao – 10 April 2017 – Cholesterol synthesis is regulated by the transcription factor sterol regulatory element binding protein 2 (SREBP‐2) and its target gene 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase (HMGCR), which is the rate‐limiting enzyme in cholesterol synthesis.
Persisting risk of hepatocellular carcinoma after hepatitis C virus cure monitored by a liver transcriptome signature
Atsushi Ono, Nicolas Goossens, Richard S. Finn, Warren N. Schmidt, Swan N. Thung, Gene Y. Im, Yujin Hoshida, on behalf of Precision Liver Cancer Prevention Consortium – 8 April 2017
Persisting risk of hepatocellular carcinoma after hepatitis C virus cure monitored by a liver transcriptome signature
Atsushi Ono, Nicolas Goossens, Richard S. Finn, Warren N. Schmidt, Swan N. Thung, Gene Y. Im, Yujin Hoshida, on behalf of Precision Liver Cancer Prevention Consortium – 8 April 2017
The natural history of primary sclerosing cholangitis in 781 children: A multicenter, international collaboration
Mark R. Deneau, Wael El‐Matary, Pamela L. Valentino, Reham Abdou, Khaled Alqoaer, Mansi Amin, Achiya Z. Amir, Marcus Auth, Fateh Bazerbachi, Annemarie Broderick, Albert Chan, Jillian Cotter, Sylvia Doan, Mounif El‐Youssef, Federica Ferrari, Katryn N. Furuya, Madeleine Gottrand, Frederic Gottrand, Nitika Gupta, Matjaz Homan, Binita M.
The natural history of primary sclerosing cholangitis in 781 children: A multicenter, international collaboration
Mark R. Deneau, Wael El‐Matary, Pamela L. Valentino, Reham Abdou, Khaled Alqoaer, Mansi Amin, Achiya Z. Amir, Marcus Auth, Fateh Bazerbachi, Annemarie Broderick, Albert Chan, Jillian Cotter, Sylvia Doan, Mounif El‐Youssef, Federica Ferrari, Katryn N. Furuya, Madeleine Gottrand, Frederic Gottrand, Nitika Gupta, Matjaz Homan, Binita M.
Glyceraldehyde‐3‐phosphate dehydrogenase promotes liver tumorigenesis by modulating phosphoglycerate dehydrogenase
Shanshan Liu, Yu Sun, Ming Jiang, Yangkai Li, Ye Tian, Weili Xue, Ninghe Ding, Yue Sun, Cheng Cheng, Jianshuang Li, Xiaoping Miao, Xinran Liu, Ling Zheng, Kun Huang – 7 April 2017 – Up‐regulated glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) is observed in multiple cancers with unclear mechanism. Using GAPDH transgenic mouse and a mouse model of diethylnitrosamine‐induced hepatocellular carcinoma (HCC), here we show that GAPDH overexpression aggravated tumor development by activating cell proliferation and inflammation.
Hepatocellular carcinoma surveillance: Sometimes just specialists' incidental behavior?
Han Zhang, Zhen‐Li Li, Hao Xing, Meng‐Chao Wu, Tian Yang – 7 April 2017
The release of microRNA‐122 during liver preservation is associated with early allograft dysfunction and graft survival after transplantation
Jasmijn W. Selten, Cornelia J. Verhoeven, Veerle Heedfeld, Henk P. Roest, Jeroen de Jonge, Jacques Pirenne, Jos van Pelt, Jan. N. M. Ijzermans, Diethard Monbaliu, Luc J. W. van der Laan – 7 April 2017 – Early allograft dysfunction (EAD) after liver transplantation (LT) is associated with inferior graft survival. EAD is more prevalent in grafts from donation after circulatory death (DCD). However, accurate prediction of liver function remains difficult because of the lack of specific biomarkers.
Issue Information
6 April 2017