NASH‐related cirrhosis: An occult liver disease burden
Marco Arrese, Ariel E. Feldstein – 6 April 2017
Marco Arrese, Ariel E. Feldstein – 6 April 2017
Pranoti Mandrekar – 6 April 2017
Terry Cheuk‐Fung Yip, Vincent Wai‐Sun Wong – 5 April 2017
Michele Merli, Marco Frigeni, Manuel Gotti, Paolo Grossi, Raffaele Bruno, Francesco Passamonti, Luca Arcaini – 5 April 2017
Kang Ho Kim, Sungwoo Choi, Ying Zhou, Eun Young Kim, Jae Man Lee, Pradip K. Saha, Sayeepriyadarshini Anakk, David D. Moore – 5 April 2017 – The nuclear receptors farnesoid X receptor (FXR; NR1H4) and small heterodimer partner (SHP; NR0B2) play crucial roles in bile acid homeostasis. Global double knockout of FXR and SHP signaling (DKO) causes severe cholestasis and liver injury at early ages. Here, we report an unexpected beneficial impact on glucose and fatty acid metabolism in aged DKO mice, which show suppressed body weight gain and adiposity when maintained on normal chow.
Michele Merli, Marco Frigeni, Manuel Gotti, Paolo Grossi, Raffaele Bruno, Francesco Passamonti, Luca Arcaini – 5 April 2017
Isabelle Durand‐Zaleski, Julie Bulsei, Olivier Seror, Pierre Nahon – 5 April 2017
Ming‐Ling Chang, Yun‐Fan Liaw – 2 April 2017
Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Christopher F. Rose, For the US Acute Liver Failure Study Group – 2 April 2017
Tai‐Shuan Lai, Mei‐Hsuan Lee, Hwai‐I Yang, San‐Lin You, Sheng‐Nan Lu, Li‐Yu Wang, Yong Yuan, Gilbert L'Italien, Kuo‐Liong Chien, Chien‐Jen Chen, for the REVEAL‐HCV Study Group – 2 April 2017 – The association between hepatitis C virus (HCV) infection and end‐stage renal disease (ESRD) remains controversial without considering the role of HCV viral load and genotype. This study aimed to determine whether HCV RNA level and genotype affect the risk of developing ESRD.