Reina Sasaki, Pradip B. Devhare, Robert Steele, Ranjit Ray, Ratna B. Ray – 20 March 2017 – Hepatitis C virus (HCV)–mediated chronic liver disease is a serious health problem around the world and often causes fibrosis/cirrhosis and hepatocellular carcinoma. The mechanism of liver disease progression during HCV infection is still unclear, although inflammation is believed to be an important player in disease pathogenesis. We previously reported that macrophages including Kupffer cells exposed to HCV induce proinflammatory cytokines.

Alain Braillon – 20 March 2017

Duminda Suraweera, Sammy Saab – 20 March 2017

Søren Møller, Jens D. Hove – 20 March 2017

Duminda Suraweera, Sammy Saab – 20 March 2017

Fu‐Ming Chang, Yen‐Po Wang, Hui‐Chu Lang, Chia‐Fen Tsai, Ming‐Chih Hou, Fa‐Yauh Lee, Ching‐Liang Lu – 20 March 2017 – Statin use decreases the risk of decompensation and mortality in patients with cirrhosis due to hepatitis C virus (HCV). Whether this beneficial effect can be extended to cirrhosis in the general population or cirrhosis due to other causes, such as hepatitis B virus (HBV) infection or alcohol, remains unknown. Statin use also decreases the risk of hepatocellular carcinoma (HCC) in patients with chronic HBV and HCV infection.

Elsa Solà, Santiago Sanchez‐Cabús, Ezequiel Rodriguez, Chiara Elia, Raquel Cela, Rebeca Moreira, Elisa Pose, Jordi Sánchez‐Delgado, Nuria Cañete, Manuel Morales‐Ruiz, Francisco Campos, Jaume Balust, Mónica Guevara, Juan Carlos García‐Valdecasas, Pere Ginès – 20 March 2017 – The alfapump system has been proposed as a new treatment for the management of refractory ascites. The system removes ascites from the peritoneal cavity to urinary bladder, producing a continuous low‐volume paracentesis.

Giovanni Musso, Roberto Gambino – 20 March 2017

Pierre Nahon, Olivier Seror, Isabelle Durand‐Zaleski – 20 March 2017

Marianna Hösel, Anke Huber, Susanne Bohlen, Julie Lucifora, Giuseppe Ronzitti, Francesco Puzzo, Florence Boisgerault, Ulrich T. Hacker, Wilhelmus J. Kwanten, Nora Klöting, Matthias Blüher, Alexander Gluschko, Michael Schramm, Olaf Utermöhlen, Wilhelm Bloch, Federico Mingozzi, Oleg Krut, Hildegard Büning – 20 March 2017 – Use of adeno‐associated viral (AAV) vectors for liver‐directed gene therapy has shown considerable success, particularly in patients with severe hemophilia B.