Excretion of infectious hepatitis E virus into milk in cows imposes high risks of zoonosis

Fen Huang, Yunlong Li, Wenhai Yu, Shenrong Jing, Jue Wang, Feiyan Long, Zhanlong He, Chenchen Yang, Yanhong Bi, Wentao Cao, Chengbo Liu, Xiuguo Hua, Qiuwei Pan – 10 June 2016 – Hepatitis E virus (HEV) represents the main cause of acute hepatitis worldwide. HEV infection in immunocompromised patients involves a high risk for the development of chronic hepatitis. Because HEV is recognized as a zoonotic pathogen, it is currently believed that swine is the primary reservoir.

Excretion of infectious hepatitis E virus into milk in cows imposes high risks of zoonosis

Fen Huang, Yunlong Li, Wenhai Yu, Shenrong Jing, Jue Wang, Feiyan Long, Zhanlong He, Chenchen Yang, Yanhong Bi, Wentao Cao, Chengbo Liu, Xiuguo Hua, Qiuwei Pan – 10 June 2016 – Hepatitis E virus (HEV) represents the main cause of acute hepatitis worldwide. HEV infection in immunocompromised patients involves a high risk for the development of chronic hepatitis. Because HEV is recognized as a zoonotic pathogen, it is currently believed that swine is the primary reservoir.

LiverLearning®: 2016 Webinar: Fibrates in the Context of Cholestatic Diseases

Webinar hosted by the Cholestatic and Biliary Diseases Special Interest group on June 9, 2016.Olivier Barbier (Moderator) Carlo Spirli (Moderator) Cynthia Levy Cynthia Levy, MD, FAASLD is a Professor of Medicine in the Division of Digestive Health and Liver Diseases and is the Associate Director of the Schiff Center for Liver Diseases at the University of Miami. She was awarded the Arthur Hertz Endowed Chair in Liver Diseases. Dr. Levy received her M.D. from Universidade Federal do Rio de Janeiro (UFRJ).

Complete hepatitis B virus prophylaxis withdrawal in hepatitis B surface antigen–positive liver transplant recipients after longterm minimal immunosuppression

Ilaria Lenci, Leonardo Baiocchi, Laura Tariciotti, Daniele Di Paolo, Martina Milana, Francesco Santopaolo, Tommaso Maria Manzia, Luca Toti, Valentina Svicher, Giuseppe Tisone, Carlo Federico Perno, Mario Angelico – 7 June 2016 – Tailored approaches have been attempted to prevent hepatitis B virus (HBV) reinfection in antibodies against hepatitis B surface antigen (HBsAg)–positive liver transplantation (LT) recipients in order to minimize the use of hepatitis B immune globulin (HBIG) and nucleoside analogues (NAs).

A highly specific and sensitive hepatitis C virus antigen enzyme immunoassay for One‐step diagnosis of viremic hepatitis C virus infection

Ke‐Qin Hu, Wei Cui – 6 June 2016 – The current standard in diagnosing hepatitis C virus (HCV) infection requires two sequential steps: anti‐HCV test to screen, followed by HCV RNA reverse‐transcription polymerase chain reaction to confirm viremic HCV (V‐HCV) infection. HCV core antigen tests provided potential for possible one‐step diagnosis. However, low sensitivity and specificity limit their clinical utility.

Recurrence of autoimmune liver disease and inflammatory bowel disease after pediatric liver transplantation

Rodrigo Liberal, Diego Vergani, Giorgina Mieli‐Vergani – 3 June 2016 – Approximately 10% of children with autoimmune hepatitis (AIH) and 30% of those with sclerosing cholangitis (SC) require liver transplantation (LT). LT is indicated in patients who present with fulminant hepatic failure (ie, with encephalopathy) and in those who develop end‐stage liver disease despite treatment. After LT, recurrent AIH is reported in approximately 30% of patients and recurrent SC in up to 50%.

Splenectomy is not indicated in living donor liver transplantation

Kyoji Ito, Nobuhisa Akamatsu, Akihiko Ichida, Daisuke Ito, Junichi Kaneko, Junichi Arita, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo – 2 June 2016 – Simultaneous splenectomy (SPX) is preferentially performed in living donor liver transplantation (LDLT) to modulate portal flow; increase postoperative platelet count, especially among those with hepatitis C virus (HCV) infection; and modulate the immunologic status in ABO‐incompatible cases. The negative effects of the procedure, however, are not well established.

Subscribe to