Soona Shin, Kirk J. Wangensteen, Monica Teta‐Bissett, Yue J. Wang, Elham Mosleh‐Shirazi, Elizabeth L. Buza, Linda E. Greenbaum, Klaus H. Kaestner – 21 April 2016 – The expression of biliary/progenitor markers by hepatocellular carcinoma (HCC) is often associated with poor prognosis and stem cell‐like behaviors of tumor cells. Hepatocellular adenomas (HCAs) also often express biliary/progenitor markers and frequently act as precursor lesions for HCC. However, the cell of origin of HCA and HCC that expresses these markers remains unclear.

Jean‐François Dufour – 21 April 2016

21 April 2016

21 April 2016

Shinya Okumura, Takumi Teratani, Yasuhiro Fujimoto, Xiangdong Zhao, Tatsuaki Tsuruyama, Yuki Masano, Naoya Kasahara, Taku Iida, Shintaro Yagi, Tadahiro Uemura, Toshimi Kaido, Shinji Uemoto – 21 April 2016 – Polyamines are essential for cell growth and differentiation. They play important roles in protection from liver damage and promotion of liver regeneration. However, little is known about the effect of oral exogenous polyamine administration on liver damage and regeneration.

Adrian Kobe, Philipp Dutkowski, Beat Müllhaupt, Pierre‐Alain Clavien, Thomas Pfammatter – 20 April 2016

Jean‐Bernard Otte – 20 April 2016 – This review presents the author's personal perspective and contributions to the first steps, the development, the current status, and the remaining issues of pediatric liver transplantation (LT). Innumerable children around the world who have undergone LT have reached adulthood. The techniques have reached maturity. As shown by my own group's experience, grafts donated by living donors might provide the best short‐term and longterm results. Debate persists about the optimal immunosuppression (IS), although the place of tacrolimus remains unchallenged.

Junyan Tao, Emily Xu, Yifei Zhao, Sucha Singh, Xiaolei Li, Gabrielle Couchy, Xin Chen, Jessica Zucman‐Rossi, Maria Chikina, Satdarshan P.S. Monga – 20 April 2016 – Hepatocellular cancer (HCC) remains a significant therapeutic challenge due to its poorly understood molecular basis. In the current study, we investigated two independent cohorts of 249 and 194 HCC cases for any combinatorial molecular aberrations. Specifically we assessed for simultaneous HMET expression or hMet activation and catenin β1 gene (CTNNB1) mutations to address any concomitant Met and Wnt signaling.

Neil Mehta, Francis Y. Yao – 20 April 2016

Muthukumarassamy Rajakannu, Sameh Awad, Oriana Ciacio, Gabriella Pittau, René Adam, Antonio Sa Cunha, Denis Castaing, Didier Samuel, Maïté Lewin, Daniel Cherqui, Eric Vibert – 20 April 2016 – Hepatic artery stenosis (HAS) is a rare complication of orthotopic liver transplantation (LT). HAS could evolve into complete thrombosis and lead to graft loss, incurring significant morbidity and mortality.