Recurrence of autoimmune liver disease and inflammatory bowel disease after pediatric liver transplantation

Rodrigo Liberal, Diego Vergani, Giorgina Mieli‐Vergani – 3 June 2016 – Approximately 10% of children with autoimmune hepatitis (AIH) and 30% of those with sclerosing cholangitis (SC) require liver transplantation (LT). LT is indicated in patients who present with fulminant hepatic failure (ie, with encephalopathy) and in those who develop end‐stage liver disease despite treatment. After LT, recurrent AIH is reported in approximately 30% of patients and recurrent SC in up to 50%.

Splenectomy is not indicated in living donor liver transplantation

Kyoji Ito, Nobuhisa Akamatsu, Akihiko Ichida, Daisuke Ito, Junichi Kaneko, Junichi Arita, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo – 2 June 2016 – Simultaneous splenectomy (SPX) is preferentially performed in living donor liver transplantation (LDLT) to modulate portal flow; increase postoperative platelet count, especially among those with hepatitis C virus (HCV) infection; and modulate the immunologic status in ABO‐incompatible cases. The negative effects of the procedure, however, are not well established.

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I. Lisanne Holster, Eric T.T.L. Tjwa, Adriaan Moelker, Ernst J. Kuipers, Henk R. van Buuren – 30 May 2016

Detection of hepatitis b virus DNA in the blood of a stem cell donor after granulocyte colony‐stimulating factor treatment

Michael Punzel, Patrick Medd, Hannah Hunter, Richard Cunningham, Bryson Pottinger, Bernd Burde, Marek Widera, Annegret Quade, Gerhard Ehninger, Anna Kozlova, Helmuth Schmidt, Karin Buhrmann, Christian G. Schüttler, Dieter Glebe, Annelies Billen, Alexander H. Schmidt, Thilo Mengling, Jens Verheyen – 30 May 2016

Detection of hepatitis b virus DNA in the blood of a stem cell donor after granulocyte colony‐stimulating factor treatment

Michael Punzel, Patrick Medd, Hannah Hunter, Richard Cunningham, Bryson Pottinger, Bernd Burde, Marek Widera, Annegret Quade, Gerhard Ehninger, Anna Kozlova, Helmuth Schmidt, Karin Buhrmann, Christian G. Schüttler, Dieter Glebe, Annelies Billen, Alexander H. Schmidt, Thilo Mengling, Jens Verheyen – 30 May 2016

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