Cost‐effectiveness of active‐passive prophylaxis and antiviral prophylaxis during pregnancy to prevent perinatal hepatitis B virus infection

Lin Fan, Kwame Owusu‐Edusei, Sarah F. Schillie, Trudy V. Murphy – 28 October 2015 – In an era of antiviral treatment, reexamination of the cost‐effectiveness of strategies to prevent perinatal hepatitis B virus (HBV) transmission in the United States is needed. We used a decision tree and Markov model to estimate the cost‐effectiveness of the current U.S. strategy and two alternatives: (1) Universal hepatitis B vaccination (HepB) strategy: No pregnant women are screened for hepatitis B surface antigen (HBsAg).

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