Jana C. Mossanen, Oliver Krenkel, Can Ergen, Olivier Govaere, Anke Liepelt, Tobias Puengel, Felix Heymann, Sandra Kalthoff, Eric Lefebvre, Dirk Eulberg, Tom Luedde, Gernot Marx, Christian P. Strassburg, Tania Roskams, Christian Trautwein, Frank Tacke – 15 June 2016 – Acetaminophen (APAP, paracetamol) poisoning is a leading cause of acute liver failure (ALF) in humans and induces hepatocyte necrosis, followed by activation of the innate immune system, further aggravating liver injury. The role of infiltrating monocytes during the early phase of ALF is still ambiguous.

Aurore Besnard, Julien Gautherot, Boris Julien, Ali Tebbi, Isabelle Garcin, Isabelle Doignon, Noémie Péan, Emmanuel Gonzales, Doris Cassio, Brigitte Grosse, Bingkaï Liu, Hanaa Safya, Florent Cauchois, Lydie Humbert, Dominique Rainteau, Thierry Tordjmann – 15 June 2016 – Many regulatory pathways are involved in liver regeneration after partial hepatectomy (PH), to initiate growth, protect liver cells, and sustain remnant liver functions.

Veronica Wendy Setiawan, Daniel O. Stram, Jacqueline Porcel, Shelly C. Lu, Loïc Le Marchand, Mazen Noureddin – 15 June 2016 – Chronic liver disease (CLD) and cirrhosis are major sources of morbidity and mortality in the United States. Little is known about the epidemiology of these two diseases in ethnic minority populations in the United States. We examined the prevalence of CLD and cirrhosis by underlying etiologies among African Americans, Native Hawaiians, Japanese Americans, Latinos, and whites in the Multiethnic Cohort.

Alina Simerzin, Elina Zorde‐Khvalevsky, Mila Rivkin, Revital Adar, Jessica Zucman‐Rossi, Gabrielle Couchy, Tania Roskams, Olivier Govaere, Moshe Oren, Hilla Giladi, Eithan Galun – 15 June 2016 – The tumor suppressor p53 is a central regulator of signaling pathways that controls the cell cycle and maintains the integrity of the human genome. p53 level is regulated by mouse double minute 2 homolog (Mdm2), which marks p53 for proteasomal degradation. The p53‐Mdm2 circuitry is subjected to complex regulation by a variety of mechanisms, including microRNAs (miRNAs).

Fen Huang, Yunlong Li, Wenhai Yu, Shenrong Jing, Jue Wang, Feiyan Long, Zhanlong He, Chenchen Yang, Yanhong Bi, Wentao Cao, Chengbo Liu, Xiuguo Hua, Qiuwei Pan – 10 June 2016 – Hepatitis E virus (HEV) represents the main cause of acute hepatitis worldwide. HEV infection in immunocompromised patients involves a high risk for the development of chronic hepatitis. Because HEV is recognized as a zoonotic pathogen, it is currently believed that swine is the primary reservoir.

Jens U. Marquardt – 10 June 2016

Fen Huang, Yunlong Li, Wenhai Yu, Shenrong Jing, Jue Wang, Feiyan Long, Zhanlong He, Chenchen Yang, Yanhong Bi, Wentao Cao, Chengbo Liu, Xiuguo Hua, Qiuwei Pan – 10 June 2016 – Hepatitis E virus (HEV) represents the main cause of acute hepatitis worldwide. HEV infection in immunocompromised patients involves a high risk for the development of chronic hepatitis. Because HEV is recognized as a zoonotic pathogen, it is currently believed that swine is the primary reservoir.

Matthew J. Armstrong, Piers Gaunt, Philip N. Newsome – 10 June 2016

Wuttiporn Manatsathit, Hrishikesh Samant, Marco A. Olivera‐Martinez – 10 June 2016

Jeffrey Cui, Rohit Loomba – 10 June 2016