Hepatology highlights
Jean‐François Dufour – 10 September 2014
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Chien‐Hsieh Chiang, Kuo‐Chin Huang – 10 September 2014
Hepatology highlights
Jean‐François Dufour – 10 September 2014
Perioperative changes in nutritional parameters and impact of graft size in patients undergoing adult living donor liver transplantation
Ahmed Hammad, Toshimi Kaido, Kohei Ogawa, Yasuhiro Fujimoto, Koji Tomiyama, Akira Mori, Tadahiro Uemura, Shinji Uemoto – 10 September 2014 – Derangements of various serum biochemical nutritional/metabolic parameters are common in patients with end‐stage liver disease who undergo liver transplantation (LT). The aim of this study was to explain the benefit of LT with respect to parameter changes and to examine the impact of the graft‐to‐recipient weight ratio (GRWR) on such changes.
A score model for the continuous grading of early allograft dysfunction severity
Eugenia Pareja, Miriam Cortes, David Hervás, José Mir, Andrés Valdivieso, José V. Castell, Agustín Lahoz – 10 September 2014 – Early allograft dysfunction (EAD) dramatically influences graft and patient outcomes. A lack of consensus on an EAD definition hinders comparisons of liver transplant outcomes and management of recipients among and within centers. We sought to develop a model for the quantitative assessment of early allograft function [Model for Early Allograft Function Scoring (MEAF)] after transplantation.
Connective tissue growth factor and integrin αvβ6: A new pair of regulators critical for ductular reaction and biliary fibrosis in mice
Liya Pi, Paulette M. Robinson, Marda Jorgensen, Seh‐Hoon Oh, Alicia R. Brown, Paul H. Weinreb, Thu Le Trinh, Protopapadakis Yianni, Chen Liu, Andrew Leask, Shelia M. Violette, Edward W. Scott, Gregory S. Schultz, Bryon E. Petersen – 9 September 2014 – Connective tissue growth factor (CTGF) is a matricellular protein that mediates cell‐matrix interaction through various subtypes of integrin receptors.
ALCAT1 controls mitochondrial etiology of fatty liver diseases, linking defective mitophagy to steatosis
Li Wang, Xiaolei Liu, Jia Nie, Jun Zhang, Scot R. Kimball, Hai Zhang, Weiping J. Zhang, Leonard S. Jefferson, Zeneng Cheng, Qiuhe Ji, Yuguang Shi – 9 September 2014
Diabetes, dyslipidemia, and death from hepatocellular carcinoma in the middle‐aged and elderly
Timothy J.S. Cross – 9 September 2014
Self‐renewal of hepatoblasts under chemically defined conditions by iterative growth factor and chemical screening
Linjie Lv, Qingwang Han, Yinghao Chu, Muzi Zhang, Lin Sun, Wanguo Wei, Caixia Jin, Wenlin Li – 9 September 2014
Transmembrane serine protease TMPRSS2 activates hepatitis C virus infection
Mariko Esumi, Mariko Ishibashi, Hiromi Yamaguchi, Satomi Nakajima, Yuhi Tai, Sachiko Kikuta, Masahiko Sugitani, Tadatoshi Takayama, Maino Tahara, Makoto Takeda, Takaji Wakita – 9 September 2014 – The human liver reacts to hepatitis C virus (HCV) with a balanced response consisting of host anti‐ and proviral activities. To explore these subtle host responses, we used oligonucleotide microarrays to investigate the differential gene expression between two groups of liver samples with high and low HCV loads (>100‐fold difference).