Waiting time predicts survival after liver transplantation for hepatocellular carcinoma: A cohort study using the United Network for Organ Sharing registry

Barry Schlansky, Yiyi Chen, David L. Scott, Donald Austin, Willscott E. Naugler – 18 May 2014 – Recipients of liver transplantation (LT) for hepatocellular carcinoma (HCC) have an 8% to 20% risk of HCC recurrence. Single‐center studies suggest that a period of waiting after HCC therapy may facilitate the selection of patients at low risk for post‐LT HCC recurrence and mortality. We evaluated whether a longer waiting time after Model for End‐Stage Liver Disease (MELD) prioritization for HCC predicts longer post‐LT survival.

Three liver transplants after a single cadaveric procurement: Split liver transplantation plus domino liver transplantation, an infrequent but valid alternative for maximizing transplant sharing and applicability—report of the first Latin American case

Gabriel Gondolesi, Pablo Barros Schelotto, Esteban Halac, Pablo Romero, Marcelo Dip, Guillermo Cervio, Diego Ramisch, Francisco Klein, Silvia Niveyro, Guillermo Orce, Silvina Yantorno, Valeria Descalzi, Oscar Imventarza – 17 May 2014

Outcomes of patients with cytomegalovirus viremia at the time of liver transplantation

Jackrapong Bruminhent, Raymund R. Razonable – 17 May 2014 – Cytomegalovirus (CMV) infection has been associated with poor outcomes after liver transplantation. Whether it is safe to perform transplantation for patients with active CMV viremia is not known. Here we report the outcomes of 6 patients with CMV viremia immediately before or at the time of liver transplantation.

HepG2 cells mount an effective antiviral interferon‐lambda based innate immune response to hepatitis C virus infection

Benjamin Israelow, Christopher M. Narbus, Marion Sourisseau, Matthew J. Evans – 16 May 2014 – Hepatitis C virus (HCV) exposure leads to persistent life‐long infections characterized by chronic inflammation often developing into cirrhosis and hepatocellular carcinoma. The mechanism by which HCV remains in the liver while inducing an inflammatory and antiviral response remains unclear.

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