Changchun Cai, Hai Huang, Sean Whelan, Li Liu, Benjamin Kautza, Jason Luciano, Guoliang Wang, Guoqiang Chen, Sladjana Stratimirovic, Allan Tsung, Timothy R. Billiar, Brian S. Zuckerbraun – 3 May 2014 – Acetaminophen (APAP) toxicity is the most common cause of acute liver failure in industrialized countries. Understanding the mechanisms of APAP‐induced liver injury as well as other forms of sterile liver injury is critical to improve the care of patients. Recent studies demonstrate that danger signaling and inflammasome activation play a role in APAP‐induced injury.

Koen Vercauteren, Naomi Van Den Eede, Ahmed Atef Mesalam, Sandrine Belouzard, Maria Teresa Catanese, Dorothea Bankwitz, Flossie Wong‐Staal, Riccardo Cortese, Jean Dubuisson, Charles M. Rice, Thomas Pietschmann, Geert Leroux‐Roels, Alfredo Nicosia, Philip Meuleman – 3 May 2014 – Hepatitis C virus (HCV)‐induced endstage liver disease is currently a major indication for liver transplantation. After transplantation the donor liver inevitably becomes infected with the circulating virus.

Michael H. Levy, Sarah Larney – 3 May 2014

Sung‐Min Ahn, Se Jin Jang, Ju Hyun Shim, Deokhoon Kim, Seung‐Mo Hong, Chang Ohk Sung, Daehyun Baek, Farhan Haq, Adnan Ahmad Ansari, Sun Young Lee, Sung‐Min Chun, Seongmin Choi, Hyun‐Jeung Choi, Jongkyu Kim, Sukjun Kim, Shin Hwang, Young‐Joo Lee, Jong‐eun Lee, Wang‐rim Jung, Hye Yoon Jang, Eunho Yang, Wing‐Kin Sung, Nikki P.

Mariya L. Samoylova, Jennifer L. Dodge, Francis Y. Yao, John Paul Roberts – 3 May 2014 – In the United States, there are significant geographic disparities in the time to transplantation for patients with hepatocellular carcinoma (HCC); it is possible that rapid transplantation contributes to higher rates of posttransplant HCC recurrence because there is insufficient time for the tumor biology to manifest. In this study, we compared HCC recurrence in rapid transplant patients and their slower transplant counterparts.

Nirmala Mavila, David James, Pranavkumar Shivakumar, Marie V. Nguyen, Sarah Utley, Katrina Mak, Allison Wu, Shengmei Zhou, Larry Wang, Christopher Vendyres, Megan Groff, Kinji Asahina, Kasper S. Wang – 3 May 2014 – Biliary atresia (BA), the most common cause of end‐stage liver disease and the leading indication for pediatric liver transplantation, is associated with intrahepatic ductular reactions within regions of rapidly expanding periportal biliary fibrosis.

Gwen Murphy, Angelika Michel, Philip R. Taylor, Demetrius Albanes, Stephanie J. Weinstein, Jarmo Virtamo, Dominick Parisi, Kirk Snyder, Julia Butt, Katherine A. McGlynn, Jill Koshiol, Michael Pawlita, Gabriel Y. Lai, Christian C. Abnet, Sanford M. Dawsey, Neal D. Freedman – 2 May 2014 – Helicobacter have been detected in human bile and hepatobiliary tissue. Despite evidence that Helicobacter species promote gallstone formation and hepatobiliary tumors in laboratory studies, it remains unclear whether Helicobacter species contribute to these cancers in humans.

Tamer Abdelrahman, Joseph Hughes, Janice Main, John McLauchlan, Mark Thursz, Emma Thomson – 2 May 2014 – High rates of sexually transmitted infection and reinfection with hepatitis C virus (HCV) have recently been reported in human immunodeficiency virus (HIV)‐infected men who have sex with men and reinfection has also been described in monoinfected injecting drug users. The diagnosis of reinfection has traditionally been based on direct Sanger sequencing of samples pre‐ and posttreatment, but not on more sensitive deep sequencing techniques.

Arikichenin Olithselvan, Srinivas Rajagopala, Mukul Vij, Vivekanandan Shanmugam, Naresh Shanmugam, Mohammed Rela – 30 April 2014 – Tuberculosis (TB) is a serious disease for liver transplant recipients (LTRs). Data on post–liver transplant TB from high‐burden countries are scant. The aims of this study were to describe the prevalence of TB in LTRs from a high‐prevalence area and to analyze the risk factors for the development of post–liver transplant TB. We performed a retrospective review of our database and a case‐control study of identified cases with TB and age‐matched LTRs without TB.

Cornelia J. Verhoeven, Herold J. Metselaar, Luc J. W. Laan – 29 April 2014