Renata Pugliese, Eduardo A. Fonseca, Gilda Porta, Vera Danesi, Teresa Guimaraes, Adriana Porta, Irene K. Miura, Cristian Borges, Helry Candido, Marcel Benavides, Flavia H. Feier, Andre Godoy, Rita Antonelli Cardoso, Mario Kondo, Paulo Chapchap, Joao Seda Neto – 7 October 2013 – Ascites is the most common complication of cirrhosis and in adults it is associated with 50% mortality at 5 years if patients do not receive a liver transplant. The occurrence of hyponatremia in these patients has been associated with increased mortality on the waiting list.

Maura Fanti, Sucha Singh, Giovanna M. Ledda‐Columbano, Amedeo Columbano, Satdarshan P. Monga – 7 October 2013 – Thyroid hormone (T3), like many other ligands of the steroid/thyroid hormone nuclear receptor superfamily, is a strong inducer of liver cell proliferation in rats and mice. However, the molecular basis of its mitogenic activity, which is currently unknown, must be elucidated if its use in hepatic regenerative medicine is to be considered. F‐344 rats or C57BL/6 mice were fed a diet containing T3 for 2‐7 days.

Tetsuya Hosaka, Fumitaka Suzuki, Hiromitsu Kumada – 7 October 2013

Alan S. Wang, Ruth M. Pfeiffer, Timothy R. Morgan, Thomas R. O'Brien – 7 October 2013

Harel Dahari, Scott J. Cotler – 6 October 2013

Odilson M. Silvestre, Alberto Q. Farias, Fernando Bacal – 4 October 2013

Michael Crawford, Geoffrey McCaughan – 4 October 2013

Alberto Unzueta, Jorge Rakela – 4 October 2013 – Hepatitis E virus (HEV) infection (genotype 3) has been described in developed countries as a cause of chronic hepatitis in recipients of solid organ transplantation (SOT), with the first cases reported in 2008. Immunosuppression seems to play a major role in the pathogenesis of chronic infections. The current gold standard for the diagnosis of HEV infection is the detection of HEV RNA in serum, stools, or both.

Nobuhisa Akamatsu, Yasuhiko Sugawara, Shouichi Satou, Tetsuya Mitsui, Riki Ninomiya, Masahiko Komagome, Fumiaki Ozawa, Yoshifumi Beck – 4 October 2013 – Recent advances in liver surgery have highlighted the effects of the splenic circulation on the hepatic circulation with respect to the hepatic arterial buffer response (HABR). The aim of the present study was to investigate the actual hemodynamic effects of splenic artery embolization/ligation and splenectomy on the hepatic circulation in patients who underwent pancreaticoduodenectomy through in vivo experimental models.

Stefan Wieland, Zuzanna Makowska, Benedetta Campana, Diego Calabrese, Michael T. Dill, Josan Chung, Francis V. Chisari, Markus H. Heim – 3 October 2013 – Approximately 50% of patients with chronic hepatitis C (CHC) have ongoing expression of interferon stimulated genes (ISGs) in the liver. It is unclear why this endogenous antiviral response is inefficient in eradicating the infection. Several viral escape strategies have been identified in vitro, including inhibition of interferon (IFN) induction and ISG messenger RNA (mRNA) translation.