Role of the inflammasome in inflammatory responses and subsequent injury after hepatic ischemia‐reperfusion injury
Yoshiyuki Inoue, Yoshikazu Yasuda, Masafumi Takahashi – 21 May 2013
A multi‐method clinical monitoring procedure is the best strategy to monitoring alcohol use on the liver transplant wait list
Andrea DiMartini, Mary Amanda Dew – 21 May 2013
Decreasing Incidence of Symptomatic Epstein‐Barr Virus Disease and Posttransplant Lymphoproliferative Disorder in Pediatric Liver Transplant Recipients: Report of the Studies of Pediatric Liver Transplantation Experience
Michael R. Narkewicz, Michael Green, Stephen Dunn, Michael Millis, Susan McDiarmid, George Mazariegos, Ravinder Anand, Wanrong Yin, Studies of Pediatric Liver Transplantation Research Group – 21 May 2013 – Posttransplant lymphoproliferative disorder (PTLD) causes significant morbidity and mortality in pediatric recipients of liver transplantation (LT). Objective: Describe the incidence of PTLD and symptomatic Epstein‐Barr virus (SEBV) disease in a large multicenter cohort of children who underwent LT with a focus on the risk factors and changes in incidence over time.
Selection and outcomes of living donors with a remnant volume less than 30% after right hepatectomy
Seong Hoon Kim, Young Kyu Kim, Seung Duk Lee, Sang‐Jae Park – 21 May 2013 – The evidence for defining a safe minimal remnant volume after living donor hepatectomy is insufficient. The aim of this study was to evaluate the outcomes of living donors with a remnant/total volume ratio (RTVR) < 30% after right hepatectomy according to the following selection criteria: the preservation of the middle hepatic vein (MHV), an age < 50 years, and no or mild fatty changes in healthy adults.
Recurrent upper gastrointestinal bleeding masquerading as gastric variceal bleeding on endoscopy after liver transplantation
Ibrahim A. Hanouneh, Bradley D. Confer, Nizar N. Zein, Naim Alkhouri, Bijan Eghtesad – 21 May 2013
Respiratory risk score for the prediction of 3‐month mortality and prolonged ventilation after liver transplantation
Moritz Kleine, Florian W. R. Vondran, Kai Johanning, Kai Timrott, Hüseyin Bektas, Frank Lehner, Juergen Klempnauer, Harald Schrem – 21 May 2013 – Survival of critically ill patients is significantly affected by prolonged ventilation. The goal of this study was the development of a respiratory risk score (RRS) for the prediction of 3‐month mortality and prolonged ventilation after liver transplantation (LT). Two hundred fifty‐four consecutive LT patients from a single center were retrospectively randomized into a training group for model design and a validation group.
Deceased Donor Liver Transplantation in Infants and Small Children: Are Partial Grafts Riskier Than Whole Organs?
Ryan P. Cauley, Khashayar Vakili, Kristina Potanos, Nora Fullington, Dionne A. Graham, Jonathan A. Finkelstein, Heung Bae Kim – 21 May 2013 – Infants have the highest wait‐list mortality of all liver transplant candidates. Although previous studies have demonstrated that young children may be at increased risk when they receive partial grafts from adult and adolescent deceased donors (DDs), with few size‐matched organs available, these grafts have increasingly been used to expand the pediatric donor pool.
Randomized, multicenter trial comparing tacrolimus plus mycophenolate mofetil to tacrolimus plus steroids in hepatitis C virus–positive recipients of living donor liver transplantation
Yasutsugu Takada, Toshimi Kaido, Katsuhiro Asonuma, Hiroyuki Sakurai, Shoji Kubo, Tetsuya Kiuchi, Yukihiro Inomata, Shuji Isaji, Hayami Tsumura, Satoshi Teramukai, Yoshihiro Matsubara, Satomi Sakabayashi, Shinji Uemoto – 21 May 2013 – The purpose of this prospective, randomized, multicenter trial was to evaluate the effects of a steroid‐avoiding immunosuppression protocol on hepatitis C virus (HCV)–positive recipients of living donor liver transplantation (LDLT).
Efficacy of liver graft washout as a function of the perfusate, pressure, and temperature
Ivo C. J. H. Post, Marcel C. Dirkes, Michal Heger, Joanne Verheij, Kora M. Bruin, Dirk Korte, Roelof J. Bennink, Thomas M. Gulik – 21 May 2013 – Donor graft washout can be impaired by colloids in organ preservation solutions that increase the viscosity and agglutinative propensity of red blood cells (RBCs) and potentially decrease organ function.
Expedited liver allocation in the United States: A critical analysis
Milan Kinkhabwala, Joel Lindower, John F. Reinus, Anita L. Principe, Paul J. Gaglio – 21 May 2013 – The fate of donor livers allocated via an out‐of‐sequence expedited placement (EP) pathway has not been previously examined. We determined the originating and receiving United Network for Organ Sharing (UNOS) regions of all donor livers procured between January 1, 2010 and October 31, 2012 and placed out of sequence with UNOS bypass code 863 (EP attempt) or 898 (miscellaneous).