Kenneth S. H. Chok, James Y. Y. Fung, See Ching Chan, Tan To Cheung, William W. Sharr, Albert C. Y. Chan, Sheung Tat Fan, Chung Mau Lo – 30 January 2012 – This study investigated the outcomes of living donor liver transplantation (LDLT) for patients with preoperative type 1 hepatorenal syndrome (HRS) and acute hepatic decompensation. Prospectively collected data for 104 patients who had fulminant hepatic failure, acute decompensation of cirrhosis, or an acute flare of chronic hepatitis B were analyzed.

Gin‐Ho Lo – 30 January 2012

Hui‐Chun Huang, Sun‐Sang Wang, I‐Fang Hsin, Ching‐Chih Chang, Fa‐Yauh Lee, Han‐Chieh Lin, Chiao‐Lin Chuang, Jing‐Yi Lee, Hsian‐Guey Hsieh, Shou‐Dong Lee – 30 January 2012 – Angiogenesis in liver cirrhosis leads to splanchnic hyperemia, increased portal inflow, and portosystemic collaterals formation, which may induce lethal complications, such as gastroesophageal variceal hemorrhage and hepatic encephalopathy. Cannabinoids (CBs) inhibit angiogenesis, but the relevant influences in cirrhosis are unknown.

Riccardo Superina – 28 January 2012

Sanjeev K. Akkina, Sumeet K. Asrani, Yi Peng, Peter Stock, W. Ray Kim, Ajay K. Israni – 28 January 2012 – Because of the shortage of deceased donor organs, transplant centers accept organs from marginal deceased donors, including older donors. Organ‐specific donor risk indices have been developed to predict graft survival with various combinations of donor and recipient characteristics. Here we review the kidney donor risk index (KDRI) and the liver donor risk index (LDRI) and compare and contrast their strengths, limitations, and potential uses.

Luca Valenti, Anna Alisi, Valerio Nobili – 27 January 2012

Gennaro D'Amico, Fabio Tine – 27 January 2012

Margaret A. Scull, Alexander Ploss – 27 January 2012

Linkang Zhou, Li Xu, Jing Ye, De Li, Wenshan Wang, Xuanhe Li, Lizhen Wu, Hui Wang, Feifei Guan, Peng Li – 25 January 2012 – High levels of dietary saturated fat have been closely associated with the development of hepatic steatosis, but the factors that mediate this process remain elusive. Here, we observed that the level of cell death‐inducing DNA fragmentation factor‐alpha‐like effector a (Cidea) expression was highly correlated with the severity of hepatic steatosis in humans.

Ashley M. Lakner, Nury M. Steuerwald, Tracy L. Walling, Sriparna Ghosh, Ting Li, Iain H. McKillop, Mark W. Russo, Herbert L. Bonkovsky, Laura W. Schrum – 25 January 2012 – Hepatic stellate cell (HSC) activation is a pivotal event in initiation and progression of hepatic fibrosis and a major contributor to collagen deposition driven by transforming growth factor beta (TGF‐β). MicroRNAs (miRs), small noncoding RNAs modulating messenger RNA (mRNA) and protein expression, have emerged as key regulatory molecules in chronic liver disease.