Wai‐Kay Seto, Danny Ka‐Ho Wong, James Fung, Fung‐Yu Huang, Ching‐Lung Lai, Man‐Fung Yuen – 6 March 2013 – The profile and clinical significance of serum hepatitis B surface antigen (HBsAg) levels during long‐term nucleoside analogue (NA) therapy in chronic hepatitis B (CHB) is undetermined. From 1994 to 2002, 322 Chinese CHB patients were started on lamivudine in our center. Patients were recruited if they were continuously treated with lamivudine for at least 10 years and maintained favorable virologic responses throughout therapy (HBV DNA <2,000 IU/mL).

Gebhard Wagener, Brian Raffel, Andrew T. Young, Moury Minhaz, Jean Emond – 6 March 2013 – Early allograft dysfunction (EAD) is a serious complication after liver transplantation (LT). There is no uniform definition of EAD, and most definitions are based on arbitrary laboratory values. The aim of this study was to devise a definition of EAD that maximizes the predictive power for early death and graft failure.

Bruce A. Runyon – 5 March 2013

Diren Beyoğlu, Sandrine Imbeaud, Olivier Maurhofer, Paulette Bioulac‐Sage, Jessica Zucman‐Rossi, Jean‐François Dufour, Jeffrey R. Idle – 5 March 2013 – Hepatocellular carcinoma (HCC) is one of the commonest causes of death from cancer. A plethora of metabolomic investigations of HCC have yielded molecules in biofluids that are both up‐ and down‐regulated but no real consensus has emerged regarding exploitable biomarkers for early detection of HCC. We report here a different approach, a combined transcriptomics and metabolomics study of energy metabolism in HCC.

Riccardo Superina – 5 March 2013

Yun‐Fan Liaw – 5 March 2013

Eun Sung Park, Ju‐Seog Lee – 5 March 2013

Jens Martin Werner, Theo Heller, Ann Marie Gordon, Arlene Sheets, Averell H. Sherker, Ellen Kessler, Kathleen S. Bean, M'Lou Stevens, James Schmitt, Barbara Rehermann – 5 March 2013 – Hepatitis C virus (HCV) infection typically results in chronic disease with HCV outpacing antiviral immune responses. Here we asked whether innate immune responses are induced in healthcare workers who are exposed to small amounts of HCV, but do not develop systemic infection and acute liver disease.

Changqing Ma, Jeffrey S. Crippin, William C. Chapman, Kevin Korenblat, Neeta Vachharajani, Kristen L. Gunter, Elizabeth M. Brunt – 5 March 2013 – Hepatopulmonary syndrome (HPS) and portopulmonary hypertension (PPH) are distinct pulmonary vascular complications of cirrhosis. Little is known about possible associated hepatic histopathological features.

Laura Capitaine, Kristof Thys, Kristof Assche, Sigrid Sterckx, Guido Pennings – 5 March 2013 – For many patients, living donor liver transplantation represents their only hope of receiving a lifesaving graft. In certain (albeit rare) cases, a minor will be the only suitable donor. Living liver donation by minors has been reported in several countries. In the academic literature and professional guidelines, little attention is paid to the development of an ethical framework for this practice. The focus is frequently limited to the donation of regenerative tissues and kidneys.