Contrast‐enhanced ultrasound diagnosis of splenic artery steal syndrome after orthotopic liver transplantation

Xian‐Sheng Zhu, Yun‐Hua Gao, Sha‐Sha Wang, Qi Cheng, Yin Ling, Li Fan, Feng Huo, Miao‐Shui Pu, Peng Li – 18 April 2012 – The aim of this study was to investigate the use of contrast‐enhanced ultrasound (CEUS) for the detection of splenic artery steal syndrome (SASS) after orthotopic liver transplantation (OLT). Two hundred forty‐seven patients underwent OLT. Blood tests and color Doppler flow imaging (CDFI) were performed at various time points after the operation. CEUS and celiac angiography were used for patients suspected of having SASS.

Two immunogenic passenger dendritic cell subsets in the rat liver have distinct trafficking patterns and radiosensitivities

Bin Yu, Hisashi Ueta, Yusuke Kitazawa, Toshiya Tanaka, Kensuke Adachi, Hiromitsu Kimura, Miwa Morita, Yasushi Sawanobori, Hai Xin Qian, Tatsuhiko Kodama, Kenjiro Matsuno – 18 April 2012 – The aim of this study was to investigate the trafficking patterns, radiation sensitivities, and functions of conventional dendritic cell (DC) subsets in the rat liver in an allotransplantation setting. We examined DCs in the liver, hepatic lymph, and graft tissues and recipient secondary lymphoid organs after liver transplantation from rats treated or untreated by sublethal irradiation.

Usability of ringed polytetrafluoroethylene grafts for middle hepatic vein reconstruction during living donor liver transplantation

Shin Hwang, Dong‐Hwan Jung, Tae‐Yong Ha, Chul‐Soo Ahn, Deok‐Bog Moon, Ki‐Hun Kim, Gi‐Won Song, Gil‐Chun Park, Sung‐Won Jung, Sam‐Youl Yoon, Jung‐Man Namgoong, Chun‐Soo Park, Yo‐Han Park, Hyeong‐Woo Park, Hyo‐Jun Lee, Sung‐Gyu Lee – 18 April 2012 – Large vein allografts are suitable for middle hepatic vein (MHV) reconstruction, but their supply is often limited. Although polytetrafluoroethylene (PTFE) grafts are unlimitedly available, their long‐term patency is relatively poor.

Donor‐specific human leukocyte antigen antibodies of the immunoglobulin G3 subclass are associated with Chronic rejection and graft loss after liver transplantation

Hugo Kaneku, Jacqueline G. O'Leary, Michiko Taniguchi, Brian M. Susskind, Paul I. Terasaki, Göran B. Klintmalm – 16 April 2012 – In a previous study, we found that 92% of patients with chronic rejection had donor‐specific human leukocyte antigen antibodies (DSAs), but surprisingly, 61% of comparator patients without rejection also had DSAs. We hypothesized that immunoglobulin G (IgG) subclasses were differentially distributed between the 2 groups.

Recruitment mechanisms of primary and malignant B cells to the human liver

Shishir Shetty, Tony Bruns, Christopher J. Weston, Zania Stamataki, Ye H. Oo, Heather M. Long, Gary M. Reynolds, Guy Pratt, Paul Moss, Sirpa Jalkanen, Stefan G. Hubscher, Patricia F. Lalor, David H. Adams – 16 April 2012 – B cells are present within chronically inflamed liver tissue and recent evidence implicates them in the progression of liver disease. In addition, a large proportion of hepatic lymphomas are of B‐cell origin.

Hepatic steatosis and steatohepatitis in human immunodeficiency virus/hepatitis C virus–coinfected patients

Juan Macías, Juan Berenguer, Miguel A. Japón, José A. Girón‐González, Antonio Rivero, Luis F. López‐Cortés, Ana Moreno, Manuel Márquez, José A. Iribarren, Enrique Ortega, Pilar Miralles, Nicolás Merchante, Juan A. Pineda – 16 April 2012 – Hepatic steatosis (HS) is frequent in human immunodeficiency virus (HIV)‐ and hepatitis C virus (HCV)‐coinfected patients. Antiretroviral therapy (ART) and metabolic alterations could induce HS. However, a protective effect of ART has been reported in a paired biopsy study.

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