Significance of isolated hepatic veno‐occlusive disease/sinusoidal obstruction syndrome after liver transplantation

Mylène Sebagh, Daniel Azoulay, Bruno Roche, Emir Hoti, Vincent Karam, Elina Teicher, Laurence Bonhomme‐Faivre, Faouzi Saliba, Jean‐Charles Duclos‐Vallée, Didier Samuel – 23 February 2011 – After liver transplantation (LT), hepatic veno‐occlusive disease (VOD), which is also known as sinusoidal obstruction syndrome (SOS), has been reported initially in relation to azathioprine use and subsequently in relation to acute rejection (AR). Isolated veno‐occlusive disease (iVOD)/SOS raises some questions about its significance and especially its treatment.

Incidence of primary sclerosing cholangitis: A systematic review and meta‐analysis

Natalie A. Molodecky, Hashim Kareemi, Rohan Parab, Herman W. Barkema, Hude Quan, Robert P. Myers, Gilaad G. Kaplan – 23 February 2011 – Incidence studies of primary sclerosing cholangitis (PSC) are important for describing the disease's burden and for shedding light on the disease's etiology. The purposes of this study were to conduct a systematic review of the incidence studies of PSC with a meta‐analysis and to investigate possible geographic variations and temporal trends in the incidence of the disease.

Peginterferon with or without ribavirin has minimal effect on quality of life, behavioral/emotional, and cognitive outcomes in children

James R. Rodrigue, William Balistreri, Barbara Haber, Maureen M. Jonas, Parvathi Mohan, Jean P. Molleston, Karen F. Murray, Michael R. Narkewicz, Philip Rosenthal, Lesley J. Smith, Steven J. Lobritto, Kathleen B. Schwarz, Patricia R. Robuck, Bruce Barton, Regino P. González‐Peralta – 23 February 2011 – The aim of this study was to prospectively assess the quality of life (QOL), behavioral/emotional functioning, and cognitive status of children undergoing treatment for hepatitis C virus (HCV) infection.

Immune response to pandemic H1N1 2009 influenza a vaccination in pediatric liver transplant recipients

Wolfram Haller, Jim Buttery, Karen Laurie, Kathe Beyerle, Winita Hardikar, George Alex – 23 February 2011 – After the announcement of a worldwide pandemic in June 2009, a single dose of a monovalent pandemic H1N1 2009 influenza A (pH1N1/09) vaccine was advocated for all Australians who were 10 years and older because of excellent immunogenicity trial results for healthy children and adults. Immunocompromised patients have previously been shown to have lower seroconversion rates after routine vaccinations.

Efficacy of selective transarterial chemoembolization in inducing tumor necrosis in small (<5 cm) hepatocellular carcinomas

Rita Golfieri, Alberta Cappelli, Alessandro Cucchetti, Fabio Piscaglia, Maria Carpenzano, Eugenia Peri, Matteo Ravaioli, Antonia D'Errico‐Grigioni, Antonio Daniele Pinna, Luigi Bolondi – 23 February 2011 – Transarterial chemoembolization (TACE) is commonly used as a bridge therapy for patients awaiting liver transplantation (LT) and for downstaging patients initially not meeting the Milan criteria.

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