Lineage tracing demonstrates no evidence of cholangiocyte epithelial‐to‐mesenchymal transition in murine models of hepatic fibrosis
Andrew S. Chu, Rosalyn Diaz, Jia‐Ji Hui, Kilangsungla Yanger, Yiwei Zong, Gianfranco Alpini, Ben Z. Stanger, Rebecca G. Wells – 27 January 2011 – Whether or not cholangiocytes or their hepatic progenitors undergo an epithelial‐to‐mesenchymal transition (EMT) to become matrix‐producing myofibroblasts during biliary fibrosis is a significant ongoing controversy.