Liver infarction after transjugular intrahepatic portosystemic shunt in a liver transplant recipient
Meng Y. Wang, Darryn R. Potosky, Sandeep Khurana – 19 September 2011
Low doses of bisphenol a induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver
Alice Marmugi, Simon Ducheix, Frédéric Lasserre, Arnaud Polizzi, Alain Paris, Nathalie Priymenko, Justine Bertrand‐Michel, Thierry Pineau, Hervé Guillou, Pascal G.P. Martin, Laïla Mselli‐Lakhal – 19 September 2011 – Changes in lifestyle are suspected to have strongly influenced the current obesity epidemic.
Targeting angiogenesis in chronic liver diseases with portal hypertension: anti–placenta growth factor inhibitor or multikinase inhibitor sorafenib?
Romain Coriat, Olivier Mir, François Goldwasser, Stanislas Pol, Stanislas Chaussade – 19 September 2011
Left lobe adult‐to‐adult living donor liver transplantation: Should portal inflow modulation be added?
Yoichi Ishizaki, Seiji Kawasaki, Hiroyuki Sugo, Jiro Yoshimoto, Noriko Fujiwara, Hiroshi Imamura – 19 September 2011 – Recently, the successful application of portal inflow modulation has led to renewed interest in the use of left lobe grafts in adult‐to‐adult living donor liver transplantation (LDLT). However, data on the hepatic hemodynamics supporting portal inflow modulation are limited, and the optimal portal circulation for a liver graft is still unclear. We analyzed 42 consecutive adult‐to‐adult left lobe LDLT cases without splenectomy or a portocaval shunt.
Staging hepatic fibrosis: Computer‐aided analysis of hepatic contours on gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid‐enhanced hepatocyte‐phase magnetic resonance imaging
Satoshi Goshima, Masayuki Kanematsu, Tatsunori Kobayashi, Takahiro Furukawa, Xuejun Zhang, Hiroshi Fujita, Haruo Watanabe, Hiroshi Kondo, Noriyuki Moriyama, Kyongtae T. Bae – 19 September 2011
A biliary HCO3− umbrella constitutes a protective mechanism against bile acid‐induced injury in human cholangiocytes
Simon Hohenester, Lucas Maillette de Buy Wenniger, Coen C. Paulusma, Sandra J. van Vliet, Douglas M. Jefferson, Ronald P. Oude Elferink, Ulrich Beuers – 19 September 2011 – Human cholangiocytes are continuously exposed to millimolar levels of hydrophobic bile salt monomers. We recently hypothesized that an apical biliary HCO umbrella might prevent the protonation of biliary glycine‐conjugated bile salts and uncontrolled cell entry of the corresponding bile acids, and that defects in this biliary HCO umbrella might predispose to chronic cholangiopathies.
Benefit of initial resection of hepatocellular carcinoma followed by transplantation in case of recurrence: An intention‐to‐treat analysis
David Fuks, Safi Dokmak, Valérie Paradis, Momar Diouf, François Durand, Jacques Belghiti – 19 September 2011 – Liver resection (LR) for hepatocellular carcinoma (HCC) as the first‐line treatment in transplantable patients followed by “salvage transplantation” (ST) in case of recurrence is an attractive concept. The aim was to identify patients who gain benefit from this approach in an intention‐to‐treat study.
Activation of autophagy protects against acetaminophen‐induced hepatotoxicity
Hong‐Min Ni, Abigail Bockus, Nikki Boggess, Hartmut Jaeschke, Wen‐Xing Ding – 19 September 2011 – Autophagy can selectively remove damaged organelles, including mitochondria, and, in turn, protect against mitochondria‐damage–induced cell death. Acetaminophen (APAP) overdose can cause liver injury in animals and humans by inducing mitochondria damage and subsequent necrosis in hepatocytes. Although many detrimental mechanisms have been reported to be responsible for APAP‐induced hepatotoxicity, it is not known whether APAP can modulate autophagy to regulate hepatotoxicity in hepatocytes.
Where are we in the search for noninvasive nonalcoholic steatohepatitis biomarkers?
José M. Mato, Shelly C. Lu – 6 September 2011
Epidemiology and outcome of infections in human immunodeficiency virus/hepatitis c virus–coinfected liver transplant recipients: A FIPSE/GESIDA Prospective Cohort Study
Asunción Moreno, Carlos Cervera, Jesús Fortún, Marino Blanes, Estibalitz Montejo, Manuel Abradelo, Oscar Len, Antonio Rafecas, Pilar Martín‐Davila, Julián Torre‐Cisneros, Magdalena Salcedo, Elisa Cordero, Ricardo Lozano, Iñaki Pérez, Antonio Rimola, José M. Miró, the OLT‐HIV FIPSE Cohort Investigators – 6 September 2011 – Information about infections unrelated to acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus (HIV)–infected liver recipients is scarce.