Effect of remote ischemic preconditioning on liver ischemia/reperfusion injury using a new mouse model
Mahmoud Abu‐Amara, Shi Yu Yang, Alberto Quaglia, Peter Rowley, Niteen Tapuria, Alexander M. Seifalian, Barry J. Fuller, Brian R. Davidson – 20 January 2011 – Ischemic preconditioning of remote organs (RIPC) reduces liver ischemia/reperfusion (IR) injury in the rabbit and rat. Mice are the only species available with a large number of transgenic strains. This study describes development and validation of a mouse model of hindlimb RIPC that attenuates liver IR injury.