Ductular reactions in human liver: Diversity at the interface

Annette S. H. Gouw, Andrew D. Clouston, Neil D. Theise – 16 August 2011 – Interest in hepatic ductular reactions (DRs) has risen in recent years because of a greater appreciation of their potential roles in regeneration, fibrogenesis, and carcinogenesis. However, confusion exists because there is significant, but often unappreciated diversity at the tissue, cellular, and subcellular levels in DRs of different diseases and stages of disease.

Events in procurement as risk factors for ischemic cholangiopathy in liver transplantation using donation after cardiac death donors

C. Burcin Taner, Ilynn G. Bulatao, Darrin L. Willingham, Dana K. Perry, Lena Sibulesky, Surakit Pungpapong, Jaime Aranda‐Michel, Andrew P. Keaveny, David J. Kramer, Justin H. Nguyen – 11 August 2011 – The use of donation after cardiac death (DCD) liver grafts is controversial because of the overall increased rates of graft loss and morbidity, which are mostly related to the consequences of ischemic cholangiopathy (IC).

Surveillance of epstein‐barr virus loads in adult liver transplantation: Associations with age, sex, posttransplant times, and transplant indications

Kirsten Schaffer, Jaythoon Hassan, Anthony Staines, Suzie Coughlan, Paul Holder, Gráinne Tuite, Aiden P. McCormick, Oscar Traynor, William W. Hall, Jeff Connell – 11 August 2011 – Epstein‐Barr virus (EBV)–associated posttransplant lymphoproliferative disorder (PTLD) is a life‐threatening complication after adult orthotopic liver transplantation (AOLT).

High rate of unemployment after liver transplantation: Analysis of the United Network for Organ Sharing database

Amina Huda, Robert Newcomer, Charlene Harrington, Mary G. Blegen, Emmet B. Keeffe – 11 August 2011 – The goal of liver transplantation (LT) is to maximize the length and quality of a patient's life and facilitate his or her return to full productivity. The aims of this study were (1) to use the United Network for Organ Sharing (UNOS) data set to determine the proportions of recipients who were employed and unemployed within 24 months after LT between 2002 and 2008 and (2) to examine the factors associated with a return to employment.

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Mariëlle Verweij, Tessa M. van Ginhoven, James R. Mitchell, Wim Sluiter, Sandra van den Engel, Henk P. Roest, Elham Torabi, Jan N. M. IJzermans, Jan H. J. Hoeijmakers, Ron W. F. de Bruin – 11 August 2011

Impact of liver transplantation on the survival of patients treated for hepatorenal syndrome type 1*

Thomas D. Boyer, Arun J. Sanyal, Guadalupe Garcia‐Tsao, Frederick Regenstein, Lorenzo Rossaro, Beate Appenrodt, Veit Gülberg, Samuel Sigal, Alice S. Bexon, Peter Teuber, the Terlipressin Study Group – 11 August 2011 – The development of hepatorenal syndrome type 1 (HRS1) is associated with a poor prognosis. Liver transplantation improves this prognosis, but the degree of the improvement is unclear. Most patients receive vasoconstrictors such as terlipressin before transplantation, and this may affect the posttransplant outcomes.

Priority of candidates with hepatocellular carcinoma awaiting liver transplantation can be reduced after successful bridge therapy

Alessandro Cucchetti, Matteo Cescon, Eleonora Bigonzi, Fabio Piscaglia, Rita Golfieri, Giorgio Ercolani, Maria Cristina Morelli, Matteo Ravaioli, Antonio Daniele Pinna – 11 August 2011 – The allocation rules for patients with hepatocellular carcinoma (HCC) who are awaiting liver transplantation (LT) are a difficult issue and are continually evolving. To reduce tumor progression or down‐stage advanced disease, most transplant centers have adopted the practice of treating HCC candidates with resection or locoregional therapies.

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