Ricky Harminder Bhogal, Stuart M. Curbishley, Christopher J. Weston, David H. Adams, Simon C. Afford – 28 October 2010 – Increasing evidence shows that reactive oxygen species (ROS) may be critical mediators of liver damage during the relative hypoxia of ischemia/reperfusion injury (IRI) associated with transplant surgery or of the tissue microenvironment created as a result of chronic hepatic inflammation or infection. Much work has been focused on Kupffer cells or liver resident macrophages with respect to the generation of ROS during IRI.

Andrew J. Portal, Mark J. W. McPhail, Matthew Bruce, Iona Coltart, Andrew Slack, Roy Sherwood, Nigel D. Heaton, Debbie Shawcross, Julia A. Wendon, Michael A. Heneghan – 28 October 2010 – Postoperative acute kidney injury (AKI) increases morbidity and mortality after liver transplantation (LT). Novel methods of assessing AKI including cystatin C (CyC) and neutrophil gelatinase–associated lipocalin (NGAL) have been identified as potential markers of AKI.

Celina M. Yong, Madan Sharma, Victor Ochoa, Freddy Abnousi, John Roberts, Nathan M. Bass, Claus U. Niemann, Stephen Shiboski, Megha Prasad, Mehdi Tavakol, Thomas A. Ports, Gabriel Gregoratos, Yerem Yeghiazarians, Andrew J. Boyle – 28 October 2010 – The optimal preoperative cardiac evaluation strategy for patients with end‐stage liver disease (ESLD) undergoing liver transplantation remains unknown. Patients are frequently referred for cardiac catheterization, but the effects of coronary artery disease (CAD) on posttransplant mortality are also unknown.

Hung‐Tien Kuo, Christine Lau, Marcelo Santos Sampaio, Suphamai Bunnapradist – 28 October 2010 – Our objectives are to examine the incidence of new‐onset diabetes mellitus after transplant (NODAT) and to identify its risk factors in pediatric liver transplant recipients using the Organ Procurement and Transplant Network/United Network for Organ Sharing database. Between July 2004 and December 2008, a total of 1214 children (2‐20 years old) received their first liver transplant alone, and had at least 1 follow‐up report of posttransplant diabetic status.

Jeremy Durack, Nathan Bass, David Teitel, Robert Kerlan, John Roberts – 28 October 2010

Wei‐Chen Lee, Ching‐Song Lee, Ruey‐Shyang Soong, Chen‐Fang Lee, Ting‐Jung Wu, Hong‐Shiue Chou, Kun‐Ming Chan – 27 October 2010

Xiu‐Da Shen, Bibo Ke, Yoichiro Uchida, Haofeng Ji, Feng Gao, Yuan Zhai, Ronald W. Busuttil, Jerzy W. Kupiec‐Weglinski – 27 October 2010 – We investigated whether native macrophages overexpressing heme oxygenase 1 (HO‐1) could protect rat orthotopic liver transplant (OLT) against cold ischemia/reperfusion injury (IRI). Livers from Sprague‐Dawley rats were stored at 4°C in University of Wisconsin solution for 24 hours, and then they were transplanted into syngeneic recipients.

Alexander B. Benson, James R. Burton, Gregory L. Austin, Scott W. Biggins, Michael A. Zimmerman, Igal Kam, Susan Mandell, Christopher C. Silliman, Hugo Rosen, Marc Moss – 27 October 2010 – Patients with chronic liver disease have an increased risk of developing transfusion‐related acute lung injury (TRALI) from plasma‐containing blood products. Similarly, red blood cell transfusions have been associated with postoperative and nosocomial infections in surgical and critical care populations.

Jama M. Darling, Jeroen Aerssens, Gregory Fanning, John G. McHutchison, David B. Goldstein, Alexander J. Thompson, Kevin V. Shianna, Nezam H. Afdhal, Michael L. Hudson, Charles D. Howell, Willem Talloen, Jacques Bollekens, Mieke De Wit, Annick Scholliers, Michael W. Fried – 26 October 2010 – Polymorphisms of the IL28B gene are highly associated with sustained virological response (SVR) in patients with chronic hepatitis C treated with peginterferon and ribavirin. Quantitation of interferon‐γ–inducible protein‐10 (IP‐10) may also differentiate antiviral response.

Matthew L. Albert, Armanda Casrouge, Stéphane Chevaliez, Christophe Hézode, Isabelle Rosa, Philippe Renard, Vincent Mallet, Arnaud Fontanet, Jean‐Michel Pawlotsky, Stanislas Pol – 26 October 2010