Relationship between the pattern of hepatic iron deposition and histological severity in nonalcoholic fatty liver disease

James E. Nelson, Laura Wilson, Elizabeth M. Brunt, Matthew M. Yeh, David E. Kleiner, Aynur Unalp‐Arida, Kris V. Kowdley – 11 October 2010 – Previous studies examining the relationship between hepatic iron deposition and histological severity in nonalcoholic fatty liver disease (NAFLD) have been inconclusive. The goal of this study was to examine the relationship between hepatic iron deposition and liver histology in 849 patients enrolled in the Nonalcoholic Steatohepatitis Clinical Research Network.

Retransplantation for donor‐derived neuroendocrine tumor

Rehana Begum, Denise Harnois, Raj Satyanarayana, Murli Krishna, Kevin C. Halling, George P. Kim, Justin H. Nguyen, Andrew P. Keaveny – 11 October 2010 – Although tumor transmission through liver transplantation (LT) is a rare occurrence, the consequences can be devastating, even when a very aggressive management approach is adopted. We report the case of a donor‐derived small cell neuroendocrine tumor (NET) in a patient who underwent LT for cholangiocarcinoma. Despite locoregional therapy, chemotherapy and ultimately retransplantation, the patient died from metastases.

Metabolic syndrome in liver transplant recipients: Prevalence, risk factors, and association with cardiovascular events

Ido Laish, Marius Braun, Eytan Mor, Jaqueline Sulkes, Yael Harif, Ziv Ben Ari – 11 October 2010 – Features of metabolic syndrome are not uncommon in patients after liver transplantation. To examine the prevalence and risk factors of posttransplantation metabolic syndrome (PTMS), the files of 252 transplant recipients (mean age, 54.5 ± 2.8 years, 57.9% male) were reviewed for pretransplant and posttransplant clinical and laboratory parameters (mean follow‐up, 6.2 ± 4.4 years).

Hepatic encephalopathy is associated with posttransplant cognitive function and brain volume

Rita Garcia‐Martinez, Alex Rovira, Juli Alonso, Carlos Jacas, Macarena Simón‐Talero, Laia Chavarria, Víctor Vargas, Juan Córdoba – 11 October 2010 – Hepatic encephalopathy (HE) is a common complication of cirrhosis that is associated with brain atrophy and may participate in impaired cognitive function after liver transplantation. This study analyzes the relationship of HE with cognitive function and brain volume after transplantation.

Primary human hepatocytes on biodegradable poly(l‐lactic acid) matrices: A promising model for improving transplantation efficiency with tissue engineering

Eva Török, Marc Lutgehetmann, Jeanette Bierwolf, Stefan Melbeck, Jochen Düllmann, Bjoern Nashan, Peter X. Ma, Joerg M. Pollok – 11 October 2010 – Liver transplantation is an established treatment for acute and chronic liver disease. However, because of the shortage of donor organs, it does not fulfill the needs of all patients. Hepatocyte transplantation is promising as an alternative method for the treatment of end‐stage liver disease and as bridging therapy until liver transplantation. Our group has been working on the optimization of matrix‐based hepatocyte transplantation.

Effects of the infant stool color card screening program on 5‐year outcome of biliary atresia in taiwan

Tien‐Hau Lien, Mei‐Hwei Chang, Jia‐Feng Wu, Huey‐Ling Chen, Hung‐Chang Lee, An‐Chyi Chen, Mao‐Meng Tiao, Tzee‐Chung Wu, Yao‐Jong Yang, Chieh‐Chung Lin, Ming‐Wei Lai, Hong‐Yuan Hsu, Yen‐Hsuan Ni, the Taiwan Infant Stool Color Card Study Group – 6 October 2010 – In Taiwan, a screening system using an infant stool color card to promote the early diagnosis of biliary atresia (BA) was established in 2002. This study aimed to investigate the 5‐year outcome of BA before and after using the screening program. BA patients were divided into three cohorts according to their birth dates.

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