Jennifer R. Kramer, Christine Y. Hachem, Fasiha Kanwal, Minghua Mei, Hashem B. El‐Serag – 6 October 2010 – Coinfection with hepatitis A virus (HAV) or hepatitis B virus (HBV) in patients with chronic hepatitis C virus (HCV) is associated with increased morbidity and mortality. The Center for Medicare and Medicaid Services has identified HAV and HBV vaccination as a priority area for quality measurement in HCV. It is unclear to what extent patients with HCV meet these recommendations.

David Kershenobich, Linda Muñoz, René Malé, Jesús Gaytan, Francisco Sánchez – 6 October 2010

Li‐Ping Ye, Xin‐Li Mao – 6 October 2010

Minggang Zhang, Sheng Xu, Yanmei Han, Xuetao Cao – 6 October 2010 – The liver, a unique tolerogenic organ, is regarded as the site to trap and destroy aging erythrocytes and activated T cells. However, to date, the mechanisms for why the liver is tolerogenic and whether liver Kupffer cells (KC) are critical phagocytes for apoptotic cells (AC) contributing to the liver immunosuppression remain unclear. Here we report that KC is the main phagocyte for AC in the liver.

Weiqin Chen, Benny Chang, Lan Li, Lawrence Chan – 5 October 2010

Ricardo Moreno‐Otero, María Trapero‐Marugán, Luisa García‐Buey, Asunción García‐Sancchez – 1 October 2010

Felix Stickel, Stephan Buch, Katharina Lau, Henriette Meyer zu Schwabedissen, Thomas Berg, Monika Ridinger, Marcella Rietschel, Clemens Schafmayer, Felix Braun, Holger Hinrichsen, Rainer Günther, Alexander Arlt, Marcus Seeger, Sebastian Müller, Helmut Karl Seitz, Michael Soyka, Markus Lerch, Frank Lammert, Christoph Sarrazin, Ralf Kubitz, Dieter Häussinger, Claus Hellerbrand, Dieter Bröring, Stefan Schreiber, Falk Kiefer, Rainer Spanagel, Karl Mann, Christian Datz, Michael Krawczak, Norbert Wodarz, Henry Völzke, Jochen Hampe – 30 September 2010 – A recent genome‐wide study revealed an assoc

Stella M. Martínez, Gonzalo Crespo, Miquel Navasa, Xavier Forns – 30 September 2010 – Liver biopsy has long been an important tool for assessing the degree of liver fibrosis. Information on the presence and degree of liver fibrosis is useful before making therapeutic decisions or predicting disease outcomes. The need to stage liver fibrosis, however, should decrease as treatment options become more successful (as has occurred with viral hepatitis).

Krishna Banaudha, Michael Kaliszewski, Tamara Korolnek, Liliana Florea, Man Lung Yeung, Kuan‐Teh Jeang, Ajit Kumar – 30 September 2010 – MicroRNAs (miRNAs) are approximately 22‐nucleotide noncoding RNAs that constitute silencers of target gene expression. Aberrant expression of miRNA has been linked to a variety of cancers, including hepatocellular carcinoma (HCC). Hepatitis C virus (HCV) infection is considered a major cause of chronic liver disease and HCC, although the mechanism of virus infection–associated hepatocarcinogenesis remains unclear.

Peter J. Lewindon, Ross W. Shepherd, Meagan J. Walsh, Ristan M. Greer, Richard Williamson, Tamara N. Pereira, Kieran Frawley, Scott C. Bell, Jeffery L. Smith, Grant A. Ramm – 30 September 2010 – Cystic fibrosis liver disease (CFLD), which results from progressive hepatobiliary fibrosis, is an important cause of morbidity and mortality, but it is difficult to identify before portal hypertension (PHT) ensues.