Saffron: A potential candidate for a novel anticancer drug against hepatocellular carcinoma
Amr Amin, Alaaeldin A. Hamza, Khuloud Bajbouj, S. Salman Ashraf, Sayel Daoud – 23 May 2011 – Saffron has been proposed as a promising candidate for cancer chemoprevention. The purpose of this investigation was to investigate the chemopreventive action and the possible mechanisms of saffron against diethylnitrosamine (DEN)‐induced liver cancer in rats. Administration of saffron at doses of 75, 150, and 300 mg/kg/day was started 2 weeks prior to the DEN injection and was continued for 22 weeks.