Hepatitis C recurrence is not adversely affected by the use of donation after cardiac death liver allografts

Ran Tao, Kristine Ruppert, Ruy J. Cruz, Shahid M. Malik, Obaid Shaikh, Jawad Ahmad, Andrea DiMartini, Abhinav Humar, Paulo A. Fontes, Michael E. de Vera – 27 August 2010 – Many factors can worsen a recurrent hepatitis C virus (HCV) infection after liver transplantation (LT). We sought to determine whether the use of donation after cardiac death (DCD) livers affects HCV recurrence. From January 2000 to June 2008, 37 HCV patients underwent LT with DCD allografts.

Post–liver transplant cholestatic hepatitis C: A systematic review of clinical and pathological findings and application of consensus criteria

Tarun K. Narang, Will Ahrens, Mark W. Russo – 27 August 2010 – Liver transplantation is currently the only definitive modality for the treatment of end‐stage liver disease due to chronic hepatitis C. However, recurrent hepatitis C after liver transplantation is nearly universal. Cirrhosis may develop in 20% of recipients within 5 years, and recurrent hepatitis C may lead to graft failure, retransplantation, and even death.

Impact of obesity on children undergoing liver transplantation

André A. S. Dick, James D. Perkins, Austin L. Spitzer, Oliver B. Lao, Patrick J. Healey, Jorge D. Reyes – 27 August 2010 – Controversies exist with respect to the mortality of patients undergoing liver transplantation at the extremes of the body mass index (BMI). For pediatric liver transplantation, weight is usually the only factor considered in survival analysis. A review of the United Network for Organ Sharing database (1987‐2007) revealed 9701 pediatric patients (<18 years old) who underwent primary liver transplantation.

Risk of transmission of systemic transthyretin amyloidosis after domino liver transplantation

Laura Lladó, Carme Baliellas, Carlos Casasnovas, Isidre Ferrer, Joan Fabregat, Emilio Ramos, Jose Castellote, Jaume Torras, Xavier Xiol, Antoni Rafecas – 27 August 2010 – Recent reports of the transmission of systemic transthyretin (TTR) amyloidosis after domino liver transplantation (DLT) using grafts from patients with familial amyloid polyneuropathy (FAP) have raised concerns about the procedure. The aim of this study was to evaluate the transmission incidence of systemic TTR amyloidosis after DLT with a complete clinical, neurological, and pathological assessment.

Posttransplant bacteremia in adult living donor liver transplant recipients

Taku Iida, Toshimi Kaido, Shintaro Yagi, Atsushi Yoshizawa, Koichiro Hata, Masaki Mizumoto, Akira Mori, Yasuhiro Ogura, Fumitaka Oike, Shinji Uemoto – 27 August 2010 – Infectious complications such as bacteremia after living donor liver transplantation (LDLT) are associated with significant morbidity and mortality. We retrospectively analyzed the frequency and characteristics of posttransplant bacteremia in 181 adult LDLT recipients between April 2006 and November 2009, and we evaluated the risk factors for posttransplant bacteremia.

Long‐term survival after 67 hours of anhepatic state due to primary liver allograft nonfunction

Harendra Arora, Janine Thekkekandam, Leora Tesche, Raeshell Sweeting, David A. Gerber, Paul H. Hayashi, Kenneth Andreoni, Tomasz Kozlowski – 27 August 2010 – Primary liver allograft nonfunction immediately after transplantation poses a life‐threatening situation for the recipient. Emergency retransplantation may not be immediately possible due to organ unavailability. Total hepatectomy with temporary portacaval shunt has been described as a bridge to retransplantation when the presence of the graft appears to be harming the recipient.

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