Feasibility of ABO‐incompatible living donor liver transplantation in the rituximab era
Toru Ikegami, Ken Shirabe, Yuji Soejima, Akinobu Taketomi, Yoshihiko Maehara – 27 August 2010
Reply: Blockade of Janus kinase 2 signaling ameliorates mouse liver damage due to ischemia and reperfusion
Ricky Harminder Bhogal, Simon C. Afford – 27 August 2010
Correction
27 August 2010
Hepatitis C virus nonstructural protein 5A inhibitors: Novel target—Now for new trials and new treatment strategies
Alex J. Thompson, Paul J. Clark, John G. McHutchison – 27 August 2010
A common variant in the patatin‐like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents
Nicola Santoro, Romy Kursawe, Ebe D'Adamo, Daniel J. Dykas, Clarence K. Zhang, Allen E. Bale, Anna M. Calí, Deepak Narayan, Melissa M. Shaw, Bridget Pierpont, Mary Savoye, Derek Lartaud, Samuel Eldrich, Samuel W. Cushman, Hongyu Zhao, Gerald I. Shulman, Sonia Caprio – 27 August 2010 – The genetic factors associated with susceptibility to nonalcoholic fatty liver disease (NAFLD) in pediatric obesity remain largely unknown.
Six‐minute walk distance predicts mortality in liver transplant candidates
Elizabeth J. Carey, D. Eric Steidley, Bashar A. Aqel, Thomas J. Byrne, Kristin L. Mekeel, Jorge Rakela, Hugo E. Vargas, David D. Douglas – 27 August 2010 – The 6‐minute walk distance (6MWD) is a simple test measuring global physical function. It is commonly used to predict mortality in patients with cardiac and pulmonary diseases, but it is also useful in assessing the functional status of patients with a variety of other medical conditions.
MicroRNA‐151 and its hosting gene FAK (focal adhesion kinase) regulate tumor cell migration and spreading of hepatocellular carcinoma
Tom Luedde – 27 August 2010 – Recurrent chromosomal aberrations are often observed in hepatocellular carcinoma (HCC), but little is known about the functional non‐coding sequences, particularly microRNAs (miRNAs), at the chromosomal breakpoints in HCC. Here we show that 22 miRNAs are often amplified or deleted in HCC. MicroRNA‐151 (miR‐151), a frequently amplified miRNA on 8q24.3, is correlated with intrahepatic metastasis of HCC.
Innate immune genetic profile to predict infection risk and outcome after liver transplant
Raymund R. Razonable – 26 August 2010
Acute liver failure is associated with elevated liver stiffness and hepatic stellate cell activation
Alexander Dechêne, Jan‐Peter Sowa, Robert K. Gieseler, Christoph Jochum, Lars P. Bechmann, Amr El Fouly, Martin Schlattjan, Fuat Saner, Hideo A. Baba, Andreas Paul, Volker Dries, Margarethe Odenthal, Guido Gerken, Scott L. Friedman, Ali Canbay – 26 August 2010 – Acute liver failure (ALF) is associated with massive short‐term cell death, whereas chronic liver injury is accompanied by continuous cell death. Hepatic stellate cells (HSCs) contribute to tissue repair and liver fibrosis in chronic liver injury, although their role in ALF remains unexplained.
Clinical syndromes and consequences of antiretroviral‐related hepatotoxicity
Marina Núñez – 26 August 2010 – Highly active antiretroviral therapy (HAART)‐related hepatotoxicity complicates the management of patients infected with human immunodeficiency virus (HIV), increases medical costs, alters the prescription patterns, and affects the guideline recommendations.