Medical Treatment Vs. Transplantation in Liver Disorders
Steven Schenker – 1 January 1984
Steven Schenker – 1 January 1984
Steven Schenker – 1 January 1984
Charles S. Davidson, Raymond S. Koff – 1 January 1984
Irwin H. Rosenberg – 1 January 1984
Naoto Aoki, Michael A. Gerber, Swan N. Thung, Mei‐Ling Chen, Judith K. Christman, Peter M. Price, Christos S. Flordellis, George Acs – 1 January 1984 – Cultured 3T3 mouse fibroblasts transfected with cloned hepatitis B virus genome and DNA coding for methotrexate‐resistant dihydrofolate reductase, produce and secrete significant amounts of hepatitis B surface antigen (HBsAg).
Peter G. Mavrelis, Helmut V. Ammon, John J. Gleysteen, Richard A. Komorowski, Ursula K. Charaf – 1 January 1983 – Alcoholic liver disease is characterized by the accumulation of fat and inflammatory changes in the liver. Because free fatty acids, the precursors of triglycerides, can damage biological membranes, accumulation of free fatty acids in the liver might be in part responsible for the functional and morphological changes seen in alcoholic liver disease.
Harold O. Conn – 1 January 1983
Ruy Perez Tamayo – 1 January 1983
Earl F. Meierhenry, Boris H. Ruebner, M. Eric Gershwin, Lucy S. Hsieh, Samuel W. French – 1 January 1983 – Mallory bodies (MBs) were induced in hepatic tumors by administration for up to 85 weeks of a diet containing 10 ppm dieldrin to 50 C3H/He and 62 C57BL/6J X C3H/He B6C3F1 male mice. MBs were seen in 15 of 28 (54%) mice which developed benign hepatic tumors and 33 of 45 (73%) mice with hepatocellular carcinoma, but in only 3 of 39 (8%) mice without hepatic tumors.
Daniel Mirouze, Robert D. Zipser, Telfer B. Reynolds – 1 January 1983 – The effect of inhibitors of prostaglandin synthesis on diuretic action was examined in patients with ascites due to chronic liver disease and in normal subjects. In patients with ascites, natriuresis after 80 mg i.v. furosemide was reduced 82% by pretreatment with indomethacin. Creatinine clearance was reduced only 16%. These effects were likely due to inhibition of renal prostaglandin synthesis, since urinary prostaglandin E2 fell and there was also reduction in natriuresis with naproxen (52%).