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Reduced Clot Stability by Thromboelastography as a Potential Indicator of Procedure‐Related Bleeding in Decompensated Cirrhosis

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Alberto Zanetto, Henry M. Rinder, Marco Senzolo, Paolo Simioni, Guadalupe Garcia‐Tsao – 12 December 2020 – In patients with decompensated cirrhosis, procedure‐related bleeding is a potentially lethal complication. Routine coagulation tests such as international normalized ratio and platelet count do not predict bleeding risk. We investigated whether thromboelastography (TEG) can identify patients with cirrhosis who are at risk of procedure‐related bleeding.

A 6‐Month Report on the Impact of the Organ Procurement and Transplantation Network/United Network for Organ Sharing Acuity Circles Policy Change

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Darius Chyou, Seth Karp, Malay B. Shah, Raymond Lynch, David S. Goldberg – 12 December 2020

Acute Liver Injury With Therapeutic Doses of Acetaminophen: A Prospective Study

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Alexandre Louvet, Line Carolle Ntandja Wandji, Elise Lemaître, Marion Khaldi, Claire Lafforgue, Florent Artru, Benoît Quesnel, Guillaume Lassailly, Sébastien Dharancy, Philippe Mathurin – 11 December 2020

Posttransplant Outcomes in Older Patients With Hepatocellular Carcinoma Are Driven by Non–Hepatocellular Carcinoma Factors

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Nia Adeniji, Vinodhini Arjunan, Vijay Prabhakar, Ajitha Mannalithara, Tara Ghaziani, Aijaz Ahmed, Paul Kwo, Mindie Nguyen, Marc L. Melcher, Ronald W. Busuttil, Sander S. Florman, Brandy Haydel, Richard M. Ruiz, Goran B. Klintmalm, David D. Lee, C. Burcin Taner, Maarouf A. Hoteit, Elizabeth C. Verna, Karim J. Halazun, Amit D. Tevar, Abhinav Humar, William C. Chapman, Neeta Vachharajani, Federico Aucejo, Trevor L. Nydam, James F. Markmann, Constance Mobley, Mark Ghobrial, Alan N. Langnas, Carol A. Carney, Jennifer Berumen, Gabriel T. Schnickel, Debra L. Sudan, Johnny C.

Adenosine Diphosphate and the P2Y13 Receptor Are Involved in the Autophagic Protection of Ex Vivo Perfused Livers From Fasted Rats: Potential Benefit for Liver Graft Preservation

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Bérengère Papegay, Vincent Nuyens, Adelin Albert, Mustapha Cherkaoui‐Malki, Pierre Andreoletti, Oberdan Leo, Véronique Kruys, Jean G. Boogaerts, Joseph Vamecq – 11 December 2020 – Studies on how to protect livers perfused ex vivo can help design strategies for hepatoprotection and liver graft preservation. The protection of livers isolated from 24‐hour versus 18‐hour starved rats has been previously attributed to autophagy, which contributes to the energy‐mobilizing capacity ex vivo. Here, we explored the signaling pathways responsible for this protection.