Bertus Eksteen, Christopher L. Bowlus, Aldo J. Montano‐Loza, Eric Lefebvre, Laurent Fischer, Pamela Vig, Eduardo Bruno Martins, Jawad Ahmad, Kidist K. Yimam, Paul J. Pockros, Jordan J. Feld, Gerald Minuk, Cynthia Levy – 22 December 2020 – Primary sclerosing cholangitis (PSC) is a chronic cholestatic disease with no approved treatments. C‐C chemokine receptor types 2 and 5 (CCR2/CCR5) play an important role in inflammation and fibrosis and are potential therapeutic targets for PSC.

Sarah Wang, Juan G. Abraldes – 21 December 2020

Roniel Cabrera, Amit G. Singal, Massimo Colombo, R. Kate Kelley, Hannah Lee, Andrea R. Mospan, Tim Meyer, Pippa Newell, Neehar D. Parikh, Bruno Sangro, K. Rajender Reddy, Stephanie Watkins, Richard C. Zink, Adrian M. Di Bisceglie – 21 December 2020 – This study describes the design of the TARGET‐hepatocellular carcinoma (HCC) cohort and descriptive characteristics of the patient population at diagnosis among those who were enrolled in the cohort across academic and community clinical centers.

Yuzuru Sambommatsu, Keita Shimata, Sho Ibuki, Yasuko Narita, Kaori Isono, Masaki Honda, Tomoaki Irie, Masashi Kadohisa, Seiichi Kawabata, Hidekazu Yamamoto, Yasuhiko Sugawara, Osamu Ikeda, Yukihiro Inomata, Taizo Hibi – 21 December 2020 – Portal vein complications (PVCs) after adult living donor liver transplantation (LDLT) are potentially lethal.

Laure Elkrief, Marie Lazareth, Sylvie Chevret, Valérie Paradis, Marta Magaz, Lorraine Blaise, Laura Rubbia‐Brandt, Lucile Moga, François Durand, Audrey Payancé, Aurélie Plessier, Cendrine Chaffaut, Dominique Valla, Marion Malphettes, Alba Diaz, Jean‐Charles Nault, Pierre Nahon, Etienne Audureau, Vlad Ratziu, Laurent Castera, Juan‐Carlos Garcia Pagan, Nathalie Ganne‐Carrie, Pierre‐Emmanuel Rautou, the ANRS CO12 CirVir Group – 21 December 2020

Sarah A. Rojas, Job G. Godino, Adam Northrup, Maureen Khasira, Aaron Tam, Lisa Asmus, Catherine Frenette, Christian B. Ramers – 21 December 2020 – Hepatitis C virus (HCV) is a major cause of cirrhosis, liver cancer, and mortality in the United States. We assessed the effectiveness of decentralized HCV treatment delivered by nurse practitioners (NPs), primary care physicians (PMDs), or an infectious disease physician (ID MD) using direct‐acting antivirals in a Federally Qualified Health Center (FQHC) in urban San Diego, CA.

Teruhime Otoguro, Tomohisa Tanaka, Hirotake Kasai, Nobuhiro Kobayashi, Atsuya Yamashita, Takasuke Fukuhara, Akihide Ryo, Moto Fukai, Akinobu Taketomi, Yoshiharu Matsuura, Kohji Moriishi – 19 December 2020 – Compared with each monoinfection, coinfection with hepatitis B virus (HBV) and hepatitis C virus (HCV) is well known to increase the risks of developing liver cirrhosis and hepatocellular carcinoma. However, the mechanism by which HBV/HCV coinfection is established in hepatocytes is not well understood.

Frank A. Anania, Lara Dimick‐Santos, Ruby Mehta, Joseph Toerner, Julie Beitz – 19 December 2020

Cristina R. Bosoi, Milène Vandal, Marine Tournissac, Manon Leclerc, Hortense Fanet, Patricia L. Mitchell, Mélanie Verreault, Jocelyn Trottier, Jessica Virgili, Cynthia Tremblay, H. Robert Lippman, Jasmohan S. Bajaj, Olivier Barbier, André Marette, Frédéric Calon – 18 December 2020 – Obesity and diabetes are strongly associated not only with fatty liver but also cognitive dysfunction. Moreover, their presence, particularly in midlife, is recognized as a risk factor for Alzheimer’s disease (AD).

Tingting Jiang, Francisco J. Sánchez‐Rivera, Yadira M. Soto‐Feliciano, Qiyuan Yang, Chun‐Qing Song, Arjun Bhuatkar, Cole M Haynes, Michael T. Hemann, Wen Xue – 17 December 2020