Rechallenge After Drug-Induced Liver Injury: A Debate of the Merits and Hazards From Industry, the US Food and Drug Administration, and Clinical Academia

Hepatologists are often asked if a patient can restart a medication after an episode of DILI. Utilizing a friendly debate format, presenters highlight key points about the risk/benefit analysis in rechallenge and how to indentify patients suitable for a rechallenge trial. In addition, specific case scenarios with common medications are addressed. Given the nuances involved, the panel comprises stakeholders from academia, the pharmaceutical industry, and regulatory agencies to provide their perspective on the issue of rechallenge after DILI.

The Road to Cure and Elimination of Viral Hepatitis B and C: Breaking Barriers for Patients and Communities

The World Health Organization (WHO) has established criteria for elimination of hepatitis B and hepatitis C as public health threats by 2030. Most countries, however, are not on track to meet these WHO goals. Many patients with HBV and/or HCV infection do not have access to treatment, vaccination, or harm reduction efforts. Presenters address the main barriers to viral hepatitis elimination from patient and community perspectives, and strategies to overcome them.<br />
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American Association for the Study of Liver Diseases and North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (AASLD/NASPGHAN) Course, Part 1—Getting to the Heart of the Matter: Navigating Fontan-Associated Liver Disease

Hepatology, cardiology, and transplant medicine experts discuss the pathophysiology, clinical management, and long-term outcomes of Fontan-associated liver disease. The symposium highlights emerging research, diagnostic advancements, and multidisciplinary approaches to improve surveillance, treatment, and transplant decision-making for this unique patient population.&nbsp;Audience members learn from persuasive arguments by transplant surgeons regarding the options of isolated heart transplant versus combined heart-liver transplant for pediatric patients with Fontan failure. Attendees participate in this discussion by questioning presenters and voting how they would handle a challenging clinical case in light of the information presented.<br />
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Stump the Hepatologist

The Stump the Hepatologist session demonstrates the "art" behind the science of working through a differential diagnosis. Through live interactions with case presenters, hepatology experts work through interesting and challenging cases, voicing their thought process as the case unfolds. Participants witness how experts in the field, using their knowledge base, break down and narrow their differential diagnosis to solve the case. Following determination of the final diagnosis, each case presenter provides a brief synopsis of relevant literature.

Patient Engagement in Pediatric Liver Disease: Experiences From the A-LiNK, PFIC.org, and Starzl Networks

This session updates the community on the experience and expertise of patient engagement from 3 ongoing collaboratives:
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<li>The Autoimmune Liver Disease Network for Kids (A-LiNK) and the A-LiNK connections&nbsp;</li>
<li>PFIC.org and their Patient-Centered Outcomes Research Institute (PCORI) funded IMPACT project (<u><strong>i</strong></u>dentifying research targets by <u><strong>m</strong></u>erging <u><strong>p</strong></u>atient <u><strong>a</strong></u>nd <u><strong>c</strong></u>linician <u><strong>t</strong></u>reatment information)</li>
<li>the Starzl Network for Excellence in Pediatric Transplantation and their PCORI funded PARTNER AD<sup>3</sup>vance project&nbsp;(<u><strong>pa</strong></u>tient-centered <u><strong>r</strong></u>esearch in pediatric <u><strong>t</strong></u>ranspla<u><strong>n</strong></u>t&mdash;<u><strong>e</strong></u>ngaging families and <u><strong>r</strong></u>ecipients&mdash;<u><strong>ad</strong></u>olescent and young <u><strong>ad</strong></u>ult <u><strong>ad</strong></u>visors)</li>
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Presenters highlight the importance of patient engagement in setting research agendas, strategies for successful patient engagement, and how patient engagement affects project development and progress.

Hepatology Associates Course, Part 2: Novel Insights From Hepatology Associates

The Associates Course expands the knowledge base of participants to improve patient outcomes in behavioral, nutritional, and pharmacologic interventions in chronic liver disease. Speakers explore topics including: (1) novel treatment models of chronic hepatitis C and MASLD/MASH; (2) pharmacist driven management of chronic liver disease; (3) resource-limited management of chronic liver disease; and (4) palliative approaches to management of patients with chronic liver disease.

Artificial Intelligence: Transforming Liver Patient Care 

Artifical intelligence (AI) affects multiple areas of our lives as clinicians, researchers, and patients. This session focuses on the rapidly evolving role of AI in liver disease care. Experts address (1) the potential role of AI in predicting disease progression, treatment response, and long-term outcomes; (2) limitations and challenges in the use of AI in the liver care setting; and (3) how AI is influencing communication between clinicians and their patients.

The Liver Meeting Podcast - Tips for TIPS: A case-based discussion with Dr. Fortune and Dr. Kaplan

Join the Liver Fellows Network for a live podcast recording of&nbsp;<em>Liver Talks</em>, the official podcast of the Liver Fellow Network. In this special episode, &ldquo;Tips for TIPS&rdquo;, we will explore a complex case of portal hypertension through an engaging, case-based discussion with expert hepatologists Dr. Brett E. Fortune and Dr. David E. Kaplan.<br />
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