Boris Halgand, Christophe Desterke, Lise Rivière, Guillaume Fallot, Mylène Sebagh, Julien Calderaro, Paulette Bioulac‐Sage, Christine Neuveut, Marie‐Annick Buendia, Didier Samuel, Cyrille Féray – 12 August 2017 – Hepatitis B virus (HBV) is a major cause of hepatocellular carcinoma (HCC). However, very little is known about the replication of HBV in HCC tissues. We analyzed viral and cellular parameters in HCC (T) and nontumor liver (NT) samples from 99 hepatitis B surface antigen (HBsAg)‐positive, virologically suppressed patients treated by tumor resection or liver transplantation.

Yang‐Hsiang Lin, Meng‐Han Wu, Ya‐Hui Huang, Chau‐Ting Yeh, Mei‐Ling Cheng, Hsiang‐Cheng Chi, Chung‐Ying Tsai, I‐Hsiao Chung, Ching‐Ying Chen, Kwang‐Huei Lin – 12 August 2017 – Cancer cells display altered glucose metabolism characterized by a preference for aerobic glycolysis. The aerobic glycolytic phenotype of hepatocellular carcinoma (HCC) is often correlated with tumor progression and poorer clinical outcomes. However, the issue of whether glycolytic metabolism influences metastasis in HCC remains unclear.

Hongli Hu, Daming Gao – 12 August 2017

Meng Wang, S. Courtney Frasch, Guiying Li, Dechun Feng, Bin Gao, Liangguo Xu, Diana Ir, Daniel N. Frank, Donna L. Bratton, Cynthia Ju – 11 August 2017 – Hepatic macrophages (MΦs) are important in the development and progression of alcoholic liver disease (ALD). This study investigates the role of gp91phox (nicotinamide adenine dinucleotide phosphate oxidase 2) in the severity of ALD and specifically in regulating hepatic MΦ efferocytic capability and the subsequent reprogramming associated with resolution of inflammation.

Ryoichi Fujiwara, Ryo Mitsugi, Asuka Uemura, Tomoo Itoh, Robert H. Tukey – 10 August 2017 – Neurotoxic bilirubin is solely conjugated by UDP‐glucuronosyltransferase (UGT) 1A1. Due to an inadequate function of UGT1A1, human neonates develop mild to severe physiological hyperbilirubinemia. Accumulation of bilirubin in the brain leads to the onset of irreversible brain damage called kernicterus. Breastfeeding is one of the most significant factors that increase the risk of developing kernicterus in infants.

Katrin Hochrath, Bernd Schnabl – 6 August 2017

Timucin Taner – 5 August 2017

Francia Díaz Jaime, Marina Berenguer – 5 August 2017

Simone I. Strasser – 5 August 2017

Eyal Shemesh, Sarah Duncan, Ravinder Anand, Benjamin L. Shneider, Estella M. Alonso, George V. Mazariegos, Robert S. Venick, Rachel A. Annunziato, John C. Bucuvalas – 5 August 2017 – Knowledge of the longterm trajectory of nonadherence to immunosuppressants can inform decisions regarding organ allocation, adherence monitoring, and intervention efforts.