Marc‐Antoine Allard, Felipe Lopes, Fabio Frosio, Nicolas Golse, Antonio Sa Cunha, Daniel Cherqui, Denis Castaing, René Adam, Eric Vibert – 5 August 2017 – There is currently no tool available to predict extreme large‐for‐size (LFS) syndrome, a potentially disastrous complication after adult liver transplantation (LT). We aimed to identify the risk factors for extreme LFS and to build a simple predictive model. A cohort of consecutive patients who underwent LT with full grafts in a single institution was studied.

Henrik H. Junger, Hans J. Schlitt, Edward K. Geissler, Stefan Fichtner‐Feigl, Stefan M. Brunner – 5 August 2017 – This study aimed to elucidate the impact of epithelial regenerative responses and immune cell infiltration on biliary complications after liver transplantation. Bile duct (BD) damage after cold storage was quantified by a BD damage score and correlated with patient outcome in 41 patients. Bacterial infiltration was determined by fluorescence in situ hybridization (FISH).

Behnam Saberi, James P. Hamilton, Christine M. Durand, Zhiping Li, Benjamin Philosophe, Andrew M. Cameron, Mark S. Sulkowski, Ahmet Gurakar – 5 August 2017

Michitaka Matsuda, Shinya Tsurusaki, Naoko Miyata, Eiko Saijou, Hitoshi Okochi, Atsushi Miyajima, Minoru Tanaka – 5 August 2017 – Fibrosis is an important wound‐healing process in injured tissues, but excessive fibrosis is often observed in patients with chronic inflammation. Although oncostatin M (OSM) has been reported to play crucial roles for recovery from acute liver injury by inducing tissue inhibitor of metalloproteinase 1 (Timp1) expression, the role of OSM in chronic liver injury (CLI) is yet to be elucidated.

Hamish Innes, Andrew McAuley, Maryam Alavi, Heather Valerio, David Goldberg, Sharon J. Hutchinson – 4 August 2017 – In resource‐rich countries, chronic hepatitis C (CHC) infection is associated with a sizeable excess mortality risk. The extent to which this is due to (1) the biological sequelae of CHC infection versus (2) a high concomitant burden of health risk behaviors (HRBs) is unclear. We used data from the 1999‐2010 U.S. National Health and Nutritional Examination Surveys (NHANES), which include detailed information on HRBs and CHC infection status.

Siddharth Singh, Rohit Loomba – 4 August 2017

Haiyan Zhang, Min Lian, Jun Zhang, Zhaolian Bian, Ruqi Tang, Qi Miao, Yanshen Peng, Jingyuan Fang, Zhengrui You, Pietro Invernizzi, Qixia Wang, M. Eric Gershwin, Xiong Ma – 4 August 2017 – There is increasing awareness of the immunologic roles of liver mononuclear populations, including myeloid‐derived suppressor cells (MDSCs). We took advantage of a large well‐defined cohort of 148 patients with liver inflammation and 45 healthy controls to focus on the qualitative and quantitative characteristics of MDSCs.

Rahima A. Bhanji, Praveena Narayanan, Alina M. Allen, Harmeet Malhi, Kymberly D. Watt – 4 August 2017 – Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. Up to one third of individuals with NAFLD will develop nonalcoholic steatohepatitis (NASH), which is associated with progression to cirrhosis and is rapidly becoming the leading indication for liver transplantation. Sarcopenia is defined as a progressive and generalized loss of skeletal muscle mass, strength, and function.

Rahima A. Bhanji, Praveena Narayanan, Alina M. Allen, Harmeet Malhi, Kymberly D. Watt – 4 August 2017 – Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. Up to one third of individuals with NAFLD will develop nonalcoholic steatohepatitis (NASH), which is associated with progression to cirrhosis and is rapidly becoming the leading indication for liver transplantation. Sarcopenia is defined as a progressive and generalized loss of skeletal muscle mass, strength, and function.

Monika Sarkar, Gyorgy Baffy – 3 August 2017