HCC EV ECG score: An extracellular vesicle‐based protein assay for detection of early‐stage hepatocellular carcinoma

Na Sun, Ceng Zhang, Yi‐Te Lee, Benjamin V. Tran, Jing Wang, Hyoyong Kim, Junseok Lee, Ryan Y. Zhang, Jasmine J. Wang, Junhui Hu, Zhicheng Zhang, Manaf S. Alsudaney, Kuan‐Chu Hou, Hubert Tang, Tiffany X. Zhang, Icy Y. Liang, Ziang Zhou, Mengxiang Chen, Angela Hsiao‐Jiun Yeh, Wenyuan Li, Xianghong Jasmine Zhou, Helena R. Chang, Steven‐Huy B. Han, Saeed Sadeghi, Richard S. Finn, Sammy Saab, Ronald W. Busuttil, Mazen Noureddin, Walid S. Ayoub, Alexander Kuo, Vinay Sundaram, Buraq Al‐Ghaieb, Juvelyn Palomique, Kambiz Kosari, Irene K. Kim, Tsuyoshi Todo, Nicholas N.

Association of serum metabolites and gut microbiota at hospital admission with nosocomial infection development in patients with cirrhosis

Jasmohan S. Bajaj, K. Rajender Reddy, Puneeta Tandon, Guadalupe Garcia‐Tsao, Patrick S. Kamath, Jacqueline G. O'Leary, Florence Wong, Jennifer Lai, Hugo Vargas, Paul J. Thuluvath, Ram M. Subramanian, Marcela Pena‐Rodriguez, Masoumeh Sikaroodi, Leroy R. Thacker, Patrick M. Gillevet – 29 July 2022 – Cirrhosis is complicated by a high rate of nosocomial infections (NIs), which result in poor outcomes and are challenging to predict using clinical variables alone. Our aim was to determine predictors of NI using admission serum metabolomics and gut microbiota in inpatients with cirrhosis.

Association of changes in histologic severity of nonalcoholic steatohepatitis and changes in patient‐reported quality of life

Laura Heath, Paul Aveyard, Jeremy W. Tomlinson, Jeremy F. Cobbold, Dimitrios A. Koutoukidis – 27 July 2022 – Nonalcoholic steatohepatitis (NASH) is a prevalent chronic disease that is associated with a spectrum of liver fibrosis and can lead to cirrhosis. Patients with NASH report lower health‐related quality of life (HRQoL) than the general population. It remains uncertain how changes in histologic severity are associated with changes in HRQoL.

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